Project description:Primary objectives: Characterization of the macrophage population subset that is modulated by enteric neurons
Primary endpoints: Characterization of the macrophage population subset that is modulated by enteric neurons via RNA sequencing
Project description:To investigate the role of PexRAP/ADHAPR in adipose tissue, we use adiponectin-driven Cre recombinase to delete Dhrs7b, the gene which encodes PexRAP/ADHAPR, from all adipose depots. This study assays gene expression in subcutaneous adipose tissue (iWAT) of 8 week old chow-fed male mice.