Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Ciona intestinalis

ABSTRACT: Controlling nonlinear biological system based on network structure

PROVIDER: PRJDB6485 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	DRR110784.fastq.gz	Fastqsanger.gz
	DRR110785.fastq.gz	Fastqsanger.gz
	DRR110786.fastq.gz	Fastqsanger.gz
	DRR110787.fastq.gz	Fastqsanger.gz
	DRR110788.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 10

Similar Datasets

Ciona intestinalis

Project description:Microarray Analysis Reveals a Role of the Notch System in Ciona Siphon Regeneration

| PRJNA254952 | ENA

Gene number in an invertebrate chordate, Ciona intestinalis.

Project description:Gene number can be considered a pragmatic measure of biological complexity, but reliable data is scarce. Estimates for vertebrates are 50-100,000 genes per haploid genome, whereas invertebrate estimates fall below 25,000. We wished to test the hypothesis that the origin of vertebrates coincided with extensive gene creation. A prediction is that gene number will differ sharply between invertebrate and vertebrate members of the chordate phylum. A gene number estimation method requiring limited sequence sampling of genomic DNA was developed and validated by using data for Caenorhabditis elegans. Using the method, we estimated that the invertebrate chordate Ciona intestinalis has 15,500 protein-coding genes (+/-3,700). This number is significantly lower than gene numbers of vertebrate chordates, but similar to those of invertebrates in distantly related phyla. The data indicate that evolution of vertebrates was accompanied by a dramatic increase in protein-coding capacity of the genome.

| S-EPMC22507 | biostudies-literature

Ciona intestinalis as a model for cardiac development.

Project description:The primitive chordate Ciona intestinalis has emerged as a significant model system for the study of heart development. The Ciona embryo employs a conserved heart gene network in the context of extremely low cell numbers and reduced genetic redundancy. Here, I review recent studies on the molecular genetics of Ciona cardiogenesis as well as classic work on heart anatomy and physiology. I also discuss the potential of employing Ciona to decipher a comprehensive chordate gene network and to determine how this network controls heart morphogenesis.

| S-EPMC1857341 | biostudies-literature

Sensing charges of the Ciona intestinalis voltage-sensing phosphatase.

Project description:Voltage control over enzymatic activity in voltage-sensitive phosphatases (VSPs) is conferred by a voltage-sensing domain (VSD) located in the N terminus. These VSDs are constituted by four putative transmembrane segments (S1 to S4) resembling those found in voltage-gated ion channels. The putative fourth segment (S4) of the VSD contains positive residues that likely function as voltage-sensing elements. To study in detail how these residues sense the plasma membrane potential, we have focused on five arginines in the S4 segment of the Ciona intestinalis VSP (Ci-VSP). After implementing a histidine scan, here we show that four arginine-to-histidine mutants, namely R223H to R232H, mediate voltage-dependent proton translocation across the membrane, indicating that these residues transit through the hydrophobic core of Ci-VSP as a function of the membrane potential. These observations indicate that the charges carried by these residues are sensing charges. Furthermore, our results also show that the electrical field in VSPs is focused in a narrow hydrophobic region that separates the extracellular and intracellular space and constitutes the energy barrier for charge crossing.

| S-EPMC3813379 | biostudies-literature

Ciona intestinalis

Project description:Ciona intestinalis, Ciona roulei, and Ciona robusta raw sequence reads from ddRADseq

| PRJNA759193 | ENA

Ciona intestinalis

Project description:Gene expression profiles of unfertilized eggs of Ciona intestinalis

| PRJNA194614 | ENA

Ciona intestinalis

Project description:Ectopic expression of the Brachyury transcription factor upregulates only a subset of notochord expressed genes

| PRJNA396771 | ENA

Ciona intestinalis

Project description:Foxd ChIP-seq in Ciona embryos