Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcription profiling by high throughput sequencing of pancreatic islets from R299Q AMPK gamma 2 knock-in mice

ABSTRACT: Transcription profiling by high throughput sequencing of pancreatic islets from R299Q AMPK gamma 2 knock-in mice

PROVIDER: PRJEB11183 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR1041330_1.fastq.gz	Fastqsanger.gz
	ERR1041330_2.fastq.gz	Fastqsanger.gz
	ERR1041321_1.fastq.gz	Fastqsanger.gz
	ERR1041321_2.fastq.gz	Fastqsanger.gz
	ERR1041331_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 30

Similar Datasets

Transcription profiling by high throughput sequencing of pancreatic islets from R299Q AMPK gamma 2 knock-in mice

Project description:RNA-Seq to investigate significant transcriptional differences underlying the defective glucose-stimulated insulin secretion of R299Q AMPK g2 knock-in mice compared to wild-type littermate controls.

2016-05-20 | E-MTAB-3938 | biostudies-arrayexpress

Transcription profiling by high throughput sequencing of pancreatic islets from LKB1 and AMPK knockout mice

Project description:RNA-Seq was performed on pancreatic islets from four transgenic mouse strains affecting LKB1 and AMPK. A conditional LKB1 knockout strain was generated. Double conditional knockouts for AMPK alpha1 and AMPK alpha2 were also generated. These conditional strains were crossed with RIP-Cre (driven by rat insulin promoter) or Ins1-Cre mice to generate LKB1 knockout and AMPK double knockout strains.

2014-10-25 | E-MTAB-2791 | biostudies-arrayexpress

Transcription profiling by high throughput sequencing of pancreatic islets from LKB1 and AMPK knockout mice

Project description:Transcription profiling by high throughput sequencing of pancreatic islets from LKB1 and AMPK knockout mice

| PRJEB7122 | ENA

Gene expression in skeletal muscle in AMPK gamma3 knock-out mice and wild type littermates

Project description:Analysis of AMPK gamma3-dependent transcriptional responses by analyzing global gene expression in the white portion of the gastrocnemius muscle in AMPK gamma3 knock-out mice and corresponding wild type littermates. Keywords: Genetic modification

2006-02-15 | GSE4063 | GEO

AMPK gamma3 knock-out and mutant (R225Q) transgenic mice compared to corresponding wild type littermates

Project description:This SuperSeries is composed of the following subset Series: GSE4063: Gene expression in skeletal muscle in AMPK gamma3 knock-out mice and wild type littermates GSE4065: Gene expression in skeletal muscle in AMPK gamma3 mutant (R225Q) transgenic mice and wild type littermates. Note: GSE4063 and GSE4065 are not directly comparable. Keywords: SuperSeries Refer to individual Series

2006-02-15 | E-GEOD-4067 | biostudies-arrayexpress

Expression profiling of pancreatic islets in Tcf1 knock out mice

Project description:Expression profiling of pancreatic islets in Tcf1 knock out mice Keywords: repeat sample serie

2005-12-08 | GSE3544 | GEO

Human islets exposed to cytokines IL-1β and IFN-γ

Project description:In the context of T1 Diabetes, pro-inflammatory cytokines IL-1β and IFN-γ are known to contribute to β-cell apoptosis; The measurement of mRNA expression following β-cell exposure to these cytokines gives a picture of the changes in gene expression characterizing the path to β-cell dysfunction and death. Human islets were isolated and exposed (or not) to IL-1β and IFN-γ. The samples were collected at various time points for profiling with Affymetrix arrays. These measurements were performed three times.

2013-12-19 | E-GEOD-53454 | biostudies-arrayexpress

Human islets treated with alpha-difluoromethylornithine in combination with interferon-gamma and interleukin-beta

Project description:Proteomic data of human islets treated for 24h with alpha-difluoromethylornithine in combination with interferon-gamma and interleukin-beta; 6 biological replicates. Samples were digested with trypsin, then analyzed by LC-DIA-MS. Data was searched with FragPipe/DIA-NN.

2023-03-07 | MSV000091431 | MassIVE

Phospho-antibody microarray analyses for islets of control and Mettl14 knock-out mice

Project description:β-cell specific Mettl14 knock-out mice display reduced N6-methyladenosine (m6A) levels and recapitulate human Type II diabetes (T2D) islet phenotype with early diabetes onset and mortality secondary to decreased β-cell proliferation and insulin degranulation. To gain insights into the role of m6A in regulating the IGF1/insulin -> AKT - > PDX1 pathway and to dissect the signaling networks modulating AKT phosphorylation, we subjected freshly isolated islets from control and Mettl14 knock-out mice to phospho-antibody microarrays.

2019-08-09 | GSE132111 | GEO

High-throughput sequencing in HNRNPD knock-out and knock-in HEK293T cell lines

Project description:High-throughput sequencing in HNRNPD knock-out and knock-in HEK293T cell lines

| PRJNA877215 | ENA