Project description:Arthrobacter chlorophenolicus A6 is a 4-chlorophenol degrading soil bacterium with high phyllosphere colonization capacity. Till now the genetic basis for the phyllosphere competency of Arthrobacter or other pollutant-degrading bacteria is uncertain. We investigated global gene expression profile of A. chlorophenolicus grown in the phyllosphere of common bean (Phaseolus vulgaris) compared to growth on agar surfaces.
Project description:We compared the transcriptomic responses in the mouse white matter tissue drive white matter lesions following LPC- and L-NIO-induced injury.
Project description:Human bronchial lung cells (BEAS-2B) were treated for 6 weeks with low doses (0.5 µg/mL) of Ni and NiO nanoparticles and NiCl2. At the end of the exposure control and treated samples were submitted for RNA-Seq analysis (Hiseq2500). The overall goal of this experiment was to gain an in-depth understanding of the transcriptomic changes induced by low-dose, long-term exposure of human lung cells to Ni and NiO nanoparticles as well as to NiCl2 and to generate hypotheses related to their mechanisms of toxicity.
Project description:The understanding of host responses to Tuber colonization would facilitate the exploration of symbiotic interactions and contribute to truffle artificial cultivation. T. indicum and T. panzhihuanense were selected to colonize Pinus armandii and Carya illinoinensis for a two-and-a-half-year symbiosis experiment in this study. The molecular response of host leaf to Tuber symbiosis was analyzed using RNA-seq. T. indicum and T. panzhihuanense both triggered the defense-related regulation in host leaf, like secondary metabolism, cell wall biogenesis, plant hormone signal transduction and plant-pathogen interaction, with different patterns in P. armandii and C. illinoinensis.
Project description:Gene expression profiling of the rat lung after whole-body inhalation exposure to C60 fullerene and ultrafine nickel oxide (Uf-NiO) particles as a positive control were employed to gain insights into these molecular events.
