Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-seq of mouse and hamster oocyte and early development

ABSTRACT: We profiled the transcriptome of mouse and hamster oocytes

PROVIDER: PRJEB15293 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Transcriptional profiling of mouse and hamster oocytes

Project description:We profiled transcriptomes from mouse GV, MII oocytes and 1 cell embryos and Hamster oocytes.

2017-05-15 | GSE86470 | GEO

Transcriptional profiling of mouse and hamster oocytes

Project description:Transcriptional profiling of mouse and hamster oocytes

| PRJNA342001 | ENA

Transcriptome analysis of mouse Cnot6l-/- preovulatory oocytes (GV), ovulated eggs (MII), and 1-cell zygotes

Project description:We profiled transcriptomes from Cnot6l deadenylase knock-out mouse GV oocytes, MII eggs and 1-cell zygotes in order to analyse its function during the oocyte-to-embryo (OET) transition. Transcriptome of wild-type golden hamster GV oocytes was also profiled.

2018-07-10 | GSE116771 | GEO

Small and long RNAs profiling of testis, developing oocytes and early embryos wild-type and Pld6-deficient golden hamster

Project description:Small and long RNAs profiling of developing oocytes and early embryos in wild-type and Pld6-deficient golden hamster females, as well as profiling of testis of wild-types and Pld6-mutents

2022-02-03 | GSE195935 | GEO

Identification RBPMS2 as a key regulator in mouse early oocyte development

Project description:In the process of follicle formation, oocyte stably maintain large number of RNAs for development. However, how mammalian oocytes regulate these mRNAs, especially in the early oocyte, is unclear. We focused on RNA-binding proteins and identified RBPMS2 as a key factor in this process. Genetic disruption Rbpms2 causes female mouse infertility due to primordial oocyte defect. Transcriptome and RIP-seq analysis revealed that RBPMS2 binds 3′ UTR region to stabilize mRNAs of known oogenesis regulators, such as Lhx8. RBPMS2 also targets transcripts regulating cytoskeleton and cellular trafficking, such as Clasp1 and Rab27a, which are down-regulated in knock out oocytes. Rbpms2 knock out induces impairments in endocytosis and the accumulation of mitochondria and Golgi bodies in primordial oocyte. In summary, our study reveals RBPMS2 regulates mouse oogenesis through stabilizing mRNAs regulating oocyte development cellular trafficking and organelle enrichment, connecting post-transcriptional regulation to organelles accumulation and early oocyte development.

2026-01-16 | GSE306544 | GEO

Transcription profiling of mouse and hamster radiation hybrids to map regulatory loci for protein coding genes

Project description:We have mapped regulatory loci for nearly all protein coding genes in the mammalian genome using microarray measurements from a panel of mouse/hamster radiation hybrids. Experiment Overall Design: 99 RH cells with biological replicates (198 total) and biological replicates of mouse brain RNA vs. hamster brain RNA and mouse liver RNA vs. hamster liver RNA (4 total)

2008-04-04 | E-GEOD-9033 | biostudies-arrayexpress

Proteomic profiling of RNA binding proteins in mouse oocyte

Project description:RNA-binding proteins (RBPs) control the fate of RNAs. Tissue regeneration and homeostasis depend on tissue-specific stem cells, but the scope of RBP involvementin these processes remains largely unknown. Here, we identified the RBP repertoire of the mouse oocytes.

2023-07-20 | PXD034071 | Pride

Protein profiling of mouse fully-grown oocyte

Project description:To verify the Ribo-seq data of mouse oocyte, we performed MS/MS on mouse fully-grown oocytes. And the results show that our Ribo-seq data well reflect the proteomic dynamics in the fully grown oocytes.

2022-03-14 | PXD032229 | Pride

oocyte miRNA profiling by array

Project description:This study compares miRNA expression profiles in mouse oocytes as young oocytes vs aged oocytes, and growing oocytes vs small oocytes from primordial follicles. Oocytes were derived from the ovary of young (6-8 week-old) C57BL/6 mice and aged (41-43 week-old) mice and pooled according to whether they were 20 to 50 um or 60 to 80 um in diameter. Of oocytes with the diameter of more than 60um, oocyte from young mice are called ‘young oocytes’ and those from aged mice near the end of their reproductive life span are called ‘aged oocytes’ to analyze the miRNA profiling associated with aging. They were also each called ‘small oocytes’ or ‘large oocytes’ from the size of 60um so as to investigate miRNA profiling associated with growing. Total RNA from oocytes was isolated using mirVana miRNA Isolation Kit (Applied Biosystems). MiRNA expression was profiled using Agilent's Mouse miRNA Microarray Kit (G4472A) annotated against the Sanger miRBASE 10.1 database of miRNAs. This miRNA microarray was provided by Agilent Technologies (Santa Clara, CA). Each sample was run in duplicate.

2012-09-04 | E-GEOD-17966 | biostudies-arrayexpress

Transcriptome analysis of oocytes and early embryos to demonstrate trancriptional regulation during mouse oocyte-to-embryo transition

Project description:In this study, we performed RNA-seq to elucidate how transcriptional activities of mouse oocytes and preimplantation embryos are regulated to control oocyte-to-embryo transition. Through analyzing transcriptome alterations of transgenically-modified growing oocytes, early embryos from aged female, early embryos treated with drugs disturbing proteostasis, and embryonic stem cells treated with drugs disturbing proteostasis, we identified critical roles of proteostasis in transcriptional regulation of mouse oocytes and early embryos.

2025-01-20 | GSE241388 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data