Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Tradis POP

ABSTRACT: Simultaneous analysis of one million mutants of Salmonella Typhi

PROVIDER: PRJEB2024 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR007513.fastq.gz	Fastqsanger.gz
	ERR007514.fastq.gz	Fastqsanger.gz
	ERR007515.fastq.gz	Fastqsanger.gz
	ERR007516.fastq.gz	Fastqsanger.gz
	ERR007517.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 22

Similar Datasets

Serum challenge on a Salmonella Typhi TraDIS library

Project description:TraDIS study on Salmonella Typhi subjected to serum bactericidal assays.These data are part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/

2015-11-24 | E-ERAD-419 | biostudies-arrayexpress

S.enterica_log_vs_overnight_DNA

Project description:Gene content comparison of Salmonella enterica sv Typhimurium LT2, sv Typhi CT18 and sv Typhi TY2 cultures grown to log phase versus cultures grown overnight Keywords: parallel sample

2004-05-10 | GSE819 | GEO

Gene expression analysis of yehUT two component regulatory system

Project description:Part of a study to characterise the two component regulatory system yehUT of Salmonella enterica serovar Salmonella Typhi and Typhimurium. 24 Samples examined, 12 of strain Salmonella Typhi BRD948 and 12 of strain Salmonella Typhimurium ST4/74.

2013-09-17 | E-GEOD-50825 | biostudies-arrayexpress

TY2_hydrogen_peroxide_2mM_DNA

Project description:Gene content of Salmonella enterica sv Typhi TY2 3h after treatment with 2mM hydrogen peroxide Keywords: parallel sample

2004-05-10 | GSE824 | GEO

RNA-seq of human intestinal organoids infected with Salmonella enterica at 2.5h and 8h post infection

Project description:The purpose of this experiment was to identify intestinal epithelial responses to various strains of Salmonella enterica. Human intestinal organoids were infected with three serovars of Salmonella; Typhimurium, Enteritidis and Typhi, as well as type 3 secretion system -1 and -2 mutants in Typhimurium in order to identify host responses that were similar and unique to each serovar, and responses that were dependent on these secretion systems.

2021-10-01 | E-MTAB-10451 | biostudies-arrayexpress

Human variation impacting MCOLN2 restricts Salmonella Typhi replication by magnesium deprivation

Project description:Human genetic diversity can reveal critical factors in host-pathogen interactions. This is especially useful for human-restricted pathogens like Salmonella enterica serovar Typhi (S. Typhi), the cause of Typhoid fever. One key dynamic during infection is competition for nutrients: host cells attempt to restrict intracellular replication by depriving bacteria of key nutrients or delivering toxic metabolites in a process called nutritional immunity. Here, a cellular genome-wide association study of intracellular replication by S. Typhi in nearly a thousand cell lines from around the world—and extensive follow-up using intracellular S. Typhi transcriptomics and manipulation of magnesium concentrations—demonstrates that the divalent cation channel mucolipin-2 (MCOLN2) restricts S. Typhi intracellular replication through magnesium deprivation. Our results reveal natural diversity in Mg2+ limitation as a key component of nutritional immunity against S. Typhi.

2023-01-05 | GSE222194 | GEO

CT18_MitomycinC_2ug/ml_DNA

Project description:Gene content in Salmonella enterica sv Typhi CT18 3h after treatment with 2ug/ml Mitomycin C Keywords: repeat sample

2004-05-10 | GSE812 | GEO

Gene expression analysis of yehUT two component regulatory system

Project description:Part of a study to characterise the two component regulatory system yehUT of Salmonella enterica serovar Salmonella Typhi and Typhimurium.

2013-09-17 | GSE50825 | GEO

Comparative analysis of Salmonella Typhi, Paratyphi A, Enteritidis and Typhimurium core proteomes

Project description:Salmonella enterica subsp. enterica contains more than 2,600 serovars of which four are of major medical relevance for humans. While the typhoidal serovars (Typhi and Paratyphi A) are human-restricted and cause enteric fever, non-typhoidal Salmonella serovars (Typhimurium and Enteritidis) have a broad host range and predominantly cause gastroenteritis. In this study, we compared the core proteomes of Salmonella Typhi, Paratyphi A, Typhimurium and Enteritidis using contemporary proteomics. Five isolates, covering different geographical origins, and one reference strain per serovar were grown in vitro to the exponential phase. Protein levels of orthologous proteins between serovars were compared and subjected to gene ontology term enrichment and inferred regulatory interactions. Differential expression of the core proteomes of the typhoidal serovars appears mainly related to cell surface components and, for the non-typhoidal serovars, to pathogenicity. Our findings may guide future development of novel diagnostics and vaccines, and understanding of disease progression.

2019-05-13 | PXD011154 | Pride

Flagellin_Illumina_Microarray

Project description:the aim of the study was to assess the role of flagellin in the interaction bwetween Salmonella Typhi and host cells. A macrophage-like cell line (THP1) and an epithelial cell line (Hep2) were infected with S. Typhi expressing one of three flagellin variants: Hd, Hj or Hz66. A non-flagellated mutant (DfliC) and a non-invasive mutant (DinvA) were used as controls

2014-07-01 | E-MTAB-2395 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data