Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-seq of of bone marrow derived mononuclear phagocytes

ABSTRACT: RNA-seq of of bone marrow derived mononuclear phagocytes

PROVIDER: PRJEB26391 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR2534270_1.fastq.gz	Fastqsanger.gz
	ERR2534270_2.fastq.gz	Fastqsanger.gz
	ERR2534280_1.fastq.gz	Fastqsanger.gz
	ERR2534280_2.fastq.gz	Fastqsanger.gz
	ERR2534290_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 146

Similar Datasets

Gene expression profile of GM-CSF derived bone marrow dendritic cell subsets

2015-02-27 | GSE62361 | GEO

Gene expression profile of GM-CSF derived bone marrow dendritic cell subsets

Project description:GM-CSF derived bone marrow cultures contain several subsets of CD11c+MHCII+ mononuclear phagocytes Using Affymetrix microarrays we compared gene expression of the different mononuclear phagocytes within the bone marrow culture The Affymetrix GeneChip Mouse Gene 1.0 arrays were used to define gene expression profiles in the different population.

2015-02-27 | E-GEOD-62361 | biostudies-arrayexpress

Gene expression profile of GM-CSF derived bone marrow dendritic cell subsets after LPS stimulation

Project description:GM-CSF derived bone marrow cultures contain several subsets of CD11c+MHCII+ mononuclear phagocytes Using Affymetrix microarrays we compared gene expression of the different mononuclear phagocytes within the bone marrow culture. The different populations are left unstimulated or are stimulated with LPS

2015-09-01 | GSE62746 | GEO

Bone marrow mononuclear cells

Project description:Bone marrow mononuclear cells

| PRJNA801122 | ENA

Single-cell RNA-seq of of bone marrow derived mononuclear phagocytes derived from mouse; rat; rabbit or pig

Project description:Bone marrow derived phagocytes from mouse, rat, rabbit and pig stimulated with LPS (100ng/mL) or with dsRNA (poly I:C) (1ug/mL) for 0,2,4,6 hours. Processed files include UMI matrices of QCed cells that belong to the first cluster (as described in the publication), which were used for all the analyses presented in the publication.

2018-07-16 | E-MTAB-6754 | biostudies-arrayexpress

Gene expression profile of GM-CSF derived bone marrow dendritic cell subsets after LPS stimulation

Project description:GM-CSF derived bone marrow cultures contain several subsets of CD11c+MHCII+ mononuclear phagocytes Using Affymetrix microarrays we compared gene expression of the different mononuclear phagocytes within the bone marrow culture. The different populations are left unstimulated or are stimulated with LPS The Affymetrix GeneChip Mouse Gene 1.0 arrays were used to define gene expression profiles in the different population.

2015-09-01 | E-GEOD-62746 | biostudies-arrayexpress

Single-cell RNA-seq of of bone marrow derived mononuclear phagocytes derived from mouse rat rabbit or pig

Project description:Single-cell RNA-seq of of bone marrow derived mononuclear phagocytes derived from mouse rat rabbit or pig

| PRJEB26923 | ENA

Comparative Single Cell RNA Sequencing of Notch2 and RBPJ-deficient mononuclear phagocyte cells and myeloid progenitors from the spleen and bone marrow

Project description:Mononuclear phagocytes and their myeloid progenitors are critical in various homeostatic processes as well as immune responses. We employed single-cell RNA sequencing to investigate myeloid progenitors and mononuclear phagocytic cell subsets, including monocytes, splenic red pulp macrophages and dendritic cells in the spleen and in the bone marrow, with a focus on how Notch2 and its nuclear mediator Rbpj regulate these subsets. Our study offers a comparative analysis of mononuclear phagocytes and their progenitors examining cells isolated from the spleens or bone marrow of myeloid Notch2 (N2ΔCx3cr1)-, and Rbpj (RbpjΔCx3cr1)-deficient mice or control animals. Our findings may provide further insights into the heterogeneity of the mononuclear phagocytic cells in the spleen and bone marrow and show the critical role of Notch signaling in their development.

2025-10-30 | GSE289018 | GEO

Human iPSC-derived mononuclear phagocytes restore cognition, neural health, and a subpopulation of hippocampal mossy cells in aging mice

Project description:Young blood or plasma and young bone marrow improves cognitive function in aged animals, though the cell type responsible for these regenerative effects remains unknown. This study evaluated the potential of induced pluripotent stem cell-derived mononuclear phagocytes (iMPs) as a therapeutic for age-associated cognitive and neural decline. Aging mice receiving intravenous delivery of iMPs for 3 weeks showed significant improvements in hippocampus dependent cognitive tasks and neural health markers, including increased levels of the synaptic transporter VGLUT1 and decreases in both astrogliosis and activated microglia. Proteomics on plasma and single nuclei RNA sequencing of the hippocampus identified several key aging specific pathways. iMP treatment of aging mice was able to reverse the increases in complement and amyloid pathway proteins, restore a lost subpopulation of hippocampal mossycells, and nearly eliminate a population of activated microglia. These findings suggest that iMPs provide a novel individualized therapeutic strategy to target age-related neural decline.

2025-11-10 | PXD052723 | Pride

cecum mononuclear phagocytes

Project description:scRNAseq of cecum mononuclear phagocytes of PBS/LPS-treated mice

| PRJEB46461 | ENA