Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

MDR M. tuberculosis from the country of Georgia

ABSTRACT: MDR M. tuberculosis from the country of Georgia

PROVIDER: PRJEB39561 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR11003793_1.fastq.gz	Fastqsanger.gz
	ERR11003793_2.fastq.gz	Fastqsanger.gz
	ERR11003794_1.fastq.gz	Fastqsanger.gz
	ERR11003794_2.fastq.gz	Fastqsanger.gz
	ERR11243528_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 6399

Similar Datasets

Romanian MDR tuberculosis cohort

Project description:Romanian MDR tuberculosis cohort

| PRJNA616115 | ENA

Macrophage responses to MDR M.tuberculosis infection

Project description:The emergence of multidrug resistant (MDR) Mycobacterium tuberculosis (Mtb) strains, resistant to the frontline anti-tubercular drugs rifampicin and isoniazid, forces treatment with less effective and toxic second-line drugs and stands to derail TB control efforts. However, the immune response to MDR Mtb infection remains poorly understood. Here, we determined the RNA transcriptional profile of in vitro generated macrophages to infection with either drug susceptible Mtb HN878 or MDR Mtb W_7642 infection.

2018-12-26 | GSE115495 | GEO

Romanian MDR tuberculosis cohort

Project description:Validation Cohort for Biomarker for personalized therapy for Tuberculosis

2020-03-30 | GSE147691 | GEO

Expression data of lncRNAs and mRNAs extracted from serum of tuberculosis patients and healthy individuals

Project description:Efforts to eradicate TB are largely threatened by drug-resistant tuberculosis, particularly, multidrug-resistant tuberculosis (MDR-TB). It is imperative to find one or more specific biomarkers for diagnosing MDR-TB earlier and declining the incidence. Growing evidences have showed lncRNAs are widely expressed and take part in the genesis and development of many diseases, including tuberculosis. Therefore, to screen the differential lncRNAs among MDR-TB, drug-sensitive tuberculosis(DS-TB) and healthy controls(HCs) is a good strategy to acquire potential biomarkers for MDR-TB diagnosis and partly describe the mechanism of MDR-TB. Here, the present study aimed to investigate the differential expression profile of lncRNAs in serum among patients with MDR-TB ,DS-TB and HCs using lncRNA microarray

2021-09-10 | GSE183787 | GEO

RNA sequencing (RNA-Seq) of multi-drug resistant (MDR) cancer cells and MDR persister cancer cells.

Project description:To gain insight into the alterations of gene expression profile in the course of non-mutationally acquired resistance, we performed RNA-seq comparing MDR persister cells to MDR cancer cells.

2021-11-04 | GSE187441 | GEO

Mycobacterium tuberculosis strain:4860 | isolate:Gomel-MDR

Project description:Mycobacterium tuberculosis strain:4860 | isolate:Gomel-MDR Genome sequencing and assembly

| PRJNA625312 | ENA

Vitamin C Stimulon in Mycobacterium tuberculosis

Project description:The emergence of drug resistance among tuberculosis (TB) patients is often associated with their non-compliance to the length of the chemotherapy, which can reach up to 2 years for the treatment of multi-drug-resistant (MDR) TB. Drugs that would kill TB faster and would not lead to the development of drug resistance could shorten chemotherapy significantly. In Escherichia coli, the common mechanism of cell death by bactericidal antibiotics is the generation of highly reactive hydroxyl radicals via the Fenton reaction. Since ascorbic acid (vitamin C) is known to drive the Fenton reaction, we tested whether the Fenton reaction could lead to a bactericidal event in Mycobacterium tuberculosis by treating M. tuberculosis cultures with vitamin C. Here, we report that the addition of vitamin C to drug-susceptible, MDR and extensively drug-resistant (XDR) M. tuberculosis strains results in sterilization of the cultures in vitro. We show that the sterilizing effect of vitamin C on M. tuberculosis was dependent on the production of high ferrous ion levels and reactive oxygen species. Although, this potent sterilizing activity of vitamin C against M. tuberculosis in vitro was not observed in mice, we believe this activity needs further investigation.

2013-05-24 | GSE42293 | GEO

Vitamin C Stimulon in Mycobacterium tuberculosis

2013-05-24 | E-GEOD-42293 | biostudies-arrayexpress

Mycobacterium tuberculosis

Project description:Genome sequencing of multiple samples of Mycobacterium tuberculosis collected by OCICB TB Portals (country: Georgia)

| PRJNA1074779 | ENA

ANALYSIS OF THE GENETIC EXPRESSION PROFILES OF SENSITIVE AND MULTIPHARMACORRESISTANT Mycobacterium tuberculosis CLONES EXPOSED TO NEW COMPOUNDS

Project description:The aim of this study was to evaluate the effect of new compounds exposure on gene expression of sensitive and MDR clones of M. tuberculosis

2021-11-01 | GSE184172 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data