Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Cutibacterium modestum from a hip implant

ABSTRACT: The novel Cutibacterium modestum is a synonym of tentatively named “Cutibacterium humerusii” and often misidentified as C. acnes

PROVIDER: PRJEB41775 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR4922195_1.fastq.gz	Fastqsanger.gz
	ERR4922195_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 2 of 2

Similar Datasets

Cutibacterium modestum 28N

Project description:Cutibacterium modestum 28N Genome sequencing and assembly

| PRJNA162701 | ENA

Cutibacterium modestum 31N

Project description:Cutibacterium modestum 31N Genome sequencing and assembly

| PRJNA162705 | ENA

Cutibacterium modestum 30N

Project description:Cutibacterium modestum 30N Genome sequencing and assembly

| PRJNA162703 | ENA

Cutibacterium modestum strain:KB17-24694

Project description:Complete genome sequence of Cutibacterium modestum strain KB17-24694

| PRJDB11836 | ENA

proteomic analysis of membrane vesicles from clinical Cutibacterium acnes isolates

Project description:Recently the membrane vesicles (MVs) production has been observed in Gram-positive bacterium, Cutibacterium acnes (C. acnes). In order to explore the mechanism of antibiotic resistance and the virulent components within the C. acnes-derived MVs, we isolated MVs from the clinical C. acnes, which were sensitive or resistant to antibiotics erythromycin and clindamycin. With the LC-MS/MS method, we detected several lipases, virulent factors and cell division protein differentially expressed between the sensitive and the resistant C. acnes-derived MVs.

2022-05-20 | PXD025460 | Pride

Molecular typing and functional profiling of acne-derived Cutibacterium acnes isolates reveal determinants of skin inflammation

Project description:Cutibacterium acnes (C. acnes) is a ubiquitous skin commensal bacterium that is generally well tolerated by the immune system. Different strain-types of C. acnes have been reported to be enriched on patients with acne. To understand if these strain-types contribute to skin inflammation, we generated a library of over 200 C. acnes isolates from skin swabs of healthy and acne subjects and assessed their strain-level identity and inflammatory potential. Phylotype II K-type strains were more frequent on healthy and acne non-lesional skin compared to lesional. Phylotype IA-1 C-type strains were dominant on acne lesional skin but absent from healthy. Measurement of host cytokine responses from C. acnes supernatant revealed neither strain-type nor skin-type association predicted inflammatory potential. However, differential proinflammatory responses were induced from identical strain-types, but these differences were not attributable to protease, short chain fatty acid or porphyrin production. Instead, whole genome sequencing revealed the presence of a linear plasmid in high inflammatory strain-types. Intradermal injection of C. acnes in mouse skin revealed a plasmid-associated inflammatory response in dermal fibroblasts, revealed by single-cell RNA sequencing. We conclude that C. acnes strain-type is not sufficient to predict inflammation but other virulence factors including a plasmid may contribute to disease.

2023-08-18 | GSE211279 | GEO

Cutibacterium acnes subsp. acnes

Project description:Cutibacterium acnes subsp. acnes Assembly

| PRJNA319119 | ENA

Cutibacterium acnes

Project description:Cutibacterium acnes Genome sequencing

| PRJNA967253 | ENA

Cutibacterium acnes

Project description:Cutibacterium acnes Genome sequencing

| PRJNA967254 | ENA

Cutibacterium acnes

Project description:Cutibacterium acnes, Shoulder Arthroplasty