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TRIM28 controls the expression of the G2/M gene program and is required for mitosis execution in malignant pleural mesothelioma.

ABSTRACT: TRIM28 controls the expression of the G2/M gene program and is required for mitosis execution in malignant pleural mesothelioma.

PROVIDER: PRJEB47592 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	ERR6752040_1.fastq.gz	Fastqsanger.gz
	ERR6752040_2.fastq.gz	Fastqsanger.gz
	ERR6752041_1.fastq.gz	Fastqsanger.gz
	ERR6752041_2.fastq.gz	Fastqsanger.gz
	ERR6752042_1.fastq.gz	Fastqsanger.gz

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TRIM28 controls the expression of the G2/M gene program and is required for mitosis execution in malignant pleural mesothelioma.

Project description:The goal of this experiment was to get deep into TRIM28 biological function in malignant pleural mesothelioma. To this end MSTO-211H cell line was infected by two different sgRNAs targeting TRIM28 and a non-targeting sgRNA as control. Two independent experiments were performed.RNA was collected 7 days after infection and changes in gene expression were analyzed by mRNA-seq.

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