Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Health benefits of yogurt consumption in obese mice

ABSTRACT: The gut microbiota and fermentation-derived branched chain hydroxy acids mediate the health benefits of yogurt consumption in obese mice

PROVIDER: PRJEB47834 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR6876550.fastq.gz	Fastqsanger.gz
	ERR6876560.fastq.gz	Fastqsanger.gz
	ERR6876570.fastq.gz	Fastqsanger.gz
	ERR6876580.fastq.gz	Fastqsanger.gz
	ERR6876590.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 497

Similar Datasets

Gut microbiota and fermentation-derived branched chain hydroxy acids mediate health benefits of yogurt consumption in obese mice

Project description:Meta-analyses suggest that yogurt consumption reduces type 2 diabetes incidence in humans, but the molecular basis of these observations remains unknown. Here we show that dietary yogurt intake preserves whole-body glucose homeostasis and prevents hepatic insulin resistance and liver steatosis in a dietary mouse model of obesity-linked type 2 diabetes. Fecal microbiota transplantation studies reveal that these effects are partly linked to the gut microbiota. We further show that yogurt intake impacts the hepatic metabolome, notably maintaining the levels of branched chain hydroxy acids (BCHA) which correlate with improved metabolic parameters. These metabolites are generated upon milk fermentation and concentrated in yogurt. Remarkably, diet-induced obesity reduces plasma and tissue BCHA levels, and this is partly prevented by dietary yogurt intake. We further show that BCHA improve insulin action on glucose metabolism in liver and muscle cells, identifying BCHA as cell-autonomous metabolic regulators and potential mediators of yogurt's health effects.

2022-02-03 | MTBLS442 | MetaboLights

Ant yogurt LC-MS caseinolytic potential

Project description:Our hypothesis was that the ant holobiont may contribute enzymes, in particular proteases, that modify the yogurt texture. To test this hypothesis, we conducted an untargeted proteomics analysis based on a self-curated database that contained proteases from Formica ants, ant-yogurt bacteria, conventional yogurt bacteria, and milk proteins.

2025-08-01 | PXD057843 | Pride

Pediococcus acidilactici strain:yogurt | isolate:yogurt

Project description:Pediococcus acidilactici strain:yogurt | isolate:yogurt Genome sequencing

| PRJNA1114319 | ENA

Lactiplantibacillus plantarum strain:yogurt | isolate:yogurt

Project description:Lactiplantibacillus plantarum strain:yogurt | isolate:yogurt Genome sequencing

| PRJNA1259204 | ENA

Yogurt metagenome

Project description:Yogurt metagenome Metagenome

| PRJNA733702 | ENA

Comparison of gene expressions between LB81 yogurt-intake mice and control mice in the intestine, liver and spleen at 28 months of age

Project description:We performed the long-term administration experiment using a yogurt fermented with Lactobacillus delbrueckii subsp. bulgaricus 2038 and Streptococcus thermophilus 1131 (LB81 yogurt) for 20 months in order to understand the effects of the long-term intake of probiotics on mice. Microarrays were used to compare the gene expressions of the intestine, liver and spleen tissues between control mice and LB81 yogurt-intake mice at 28 months of age. Abbreviations used: A, LB81 yogurt-intake mice; C, control mice

2018-06-02 | GSE104375 | GEO

Gut microbiota and fermentation-derived branched chain hydroxy acids mediate health benefits of yogurt consumption in obese mice.

| S-EPMC8924213 | biostudies-literature

Transcriptomics and Metabolomics Reveal Liver Metabolic Changes and Phytochemical Deposition Occurring after Tomato Consumption in Mice

Project description:Tomato consumption is associated with many health benefits including lowered risk for developing certain cancers. However, the effects of tomato consumption on gene expression and the chemical profile of mammalian liver are not well defined.

2022-12-18 | GSE221230 | GEO

Fermentation of soy juice by Lactiplantibacillus plantarum confers a yogurt-like texture, flavours and health-promoting metabolites

Project description:The aim of the study was to decipher metabolisms responsible (i) for the peculiar adaptation of L. plantarum during soy juice fermentation and (ii) for the release of aroma compounds, amino and short-chain fatty acid, and metabolites with health-promoting properties in soy yogurt. The strategy was the sequencing and annotation of a strain (L. plantarum CIRM-BIA777, PRJEB77707) able to degrade galacto- oligosaccharides, the sampling of soy yogurt, RNA-seq to identify differentially expressed genes of L. plantarum and corresponding metabolisms throughout the kinetics of fermentation. Acids and volatile compounds were also quantified.

2024-08-18 | E-MTAB-14345 | biostudies-arrayexpress

Dried Yellow Persian Yogurt

Project description:Dried Yellow Persian Yogurt Raw sequence reads

| PRJNA530738 | ENA