Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Long-term antimicrobial resistance monitoring by phenotypic methods and metagenomics

PROVIDER: PRJEB50613 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR8314730_1.fastq.gz	Fastqsanger.gz
	ERR8314730_2.fastq.gz	Fastqsanger.gz
	ERR8314740_1.fastq.gz	Fastqsanger.gz
	ERR8314740_2.fastq.gz	Fastqsanger.gz
	ERR8314750_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 124

Similar Datasets

Project description:Antimicrobial resistance monitoring.

| PRJEB28623 | ENA

Oxidative damage and delayed replication allow viable Mycobacterium tuberculosis to go undetected [TnSeq]

Project description:“Viable but non-culturable” (VBNC) states pose challenges for environmental and clinical microbiology, but their biological mechanisms remain obscure. Mycobacterium tuberculosis (Mtb), the leading cause of death from infection until COVID-19, affords a striking example. Mtb can enter into a “differentially detectable” (DD) state associated with phenotypic antimicrobial resistance in which Mtb cells are viable but undetectable as colony-forming units. We found that Mtb cells enter the DD state when they undergo sublethal oxidative stress that damages their DNA, proteins, and lipids, and in addition, their replication is delayed, allowing repair. Mycobacterium bovis and BCG fail to enter the DD state under similar conditions. These findings have implications for TB latency, detection, relapse, treatment monitoring, and development of regimens that overcome phenotypic antimicrobial resistance.

2021-11-24 | GSE180792 | GEO

Oxidative damage and delayed replication allow viable Mycobacterium tuberculosis to go undetected II

2021-11-24 | GSE180658 | GEO

Oxidative damage and delayed replication allow viable Mycobacterium tuberculosis to go undetected

Project description:"Viable but non-culturable” (VBNC) states pose challenges for environmental and clinical microbiology, but their biological mechanisms remain obscure. Mycobacterium tuberculosis (Mtb), the leading cause of death from infection until COVID-19, affords a striking example. Mtb can enter into a “differentially detectable” (DD) state associated with phenotypic antimicrobial resistance in which Mtb cells are viable but undetectable as colony-forming units. We found that Mtb cells enter the DD state when they undergo sublethal oxidative stress that damages their DNA, proteins, and lipids, and in addition, their replication is delayed, allowing repair. Mycobacterium bovis and BCG fail to enter the DD state under similar conditions. These findings have implications for TB latency, detection, relapse, treatment monitoring, and development of regimens that overcome phenotypic antimicrobial resistance.

2021-11-24 | GSE180505 | GEO

Towards functional profiling for eDNA based monitoring in coastal environments: a comparison of three approaches

Project description:Monitoring microbial communities can aid in understanding the state of these habitats. Environmental DNA (eDNA) techniques provide efficient and comprehensive monitoring by capturing broader diversity. Besides structural profiling, eDNA methods allow the study of functional profiles, encompassing the genes within the microbial community. In this study, three methodologies were compared for functional profiling of microbial communities in estuarine and coastal sites in the Bay of Biscay. The methodologies included inference from 16S metabarcoding data using Tax4Fun, GeoChip microarrays, and shotgun metagenomics.

2024-04-14 | E-MTAB-13075 | biostudies-arrayexpress

Project description:Veterinary monitoring of antimicrobial resistance

| PRJNA1051664 | ENA

Project description:Oudekraal long term monitoring project

| PRJNA877080 | ENA

Long term bacterioplankton community trends on the South African West coast

Project description:Oudekraal long term monitoring project

| PRJEB50389 | ENA

FDA NARMS

Project description:National Antimicrobial Resistance Monitoring System (NARMS)

| PRJNA290865 | ENA

Project description:Japanese Veterinary Antimicrobial Resistance Monitoring System