Project description:To ascertain which genes are involved in the outcome of Leishmania infantum infection and immunopathology of human visceral leishmaniasis (VL), we investigated the transcriptional profile of whole blood samples from patients diagnosed with active VL compared to asymptomatic individuals (positive serology for Leishmania, but without clinical signs of disease) and healthy control samples.
Project description:Acute Myeloid Leukemia (AML) is a heterogenous disease characterized by immature blasts at different maturation stage. We used single cell sequencing technique to analyze newly diagnosed AML patients.
Project description:in this study, we aimed to determine the vesicular miRNA profile between four cohorts of BC patients according to main molecular subtypes. These samples were classified according to their age at diagnosis in two groups: Young (diagnosed before 40 years old) and Elderly (diagnosed after 40 years old). We isolated vesicular miRNA from the plasma of these patients and then assessed their miRNA levels using a high-throughput and high-resolution technique based on digital barcode hybridization.