Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Nothobranchius furzeri genome assembly

ABSTRACT: High-quality draft genome sequence of the short-lived fish Nothobranchius furzeri

PROVIDER: PRJEB5837 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
		Other
	ERR1022660_1.fastq.gz	Fastqsanger.gz
	ERR1022660_2.fastq.gz	Fastqsanger.gz
	ERR1022651_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 685

Similar Datasets

A cross-sectional study of gene expression in different strains of Nothobranchius furzeri

Project description:We quantified gene expression in three different strains of the short-lived killifish Nothobranchius furzeri during aging.

2023-10-24 | GSE207748 | GEO

RNA sequencing of gonad tissue of Nothobranchius furzeri at different age in males and females

Project description:Quantification of gene expression at different dvelopmental stages of the short-lived killifish Nothobranchius furzeri GRZ strain.

2024-04-15 | GSE263626 | GEO

Longitudinal RNA-Seq study of Nothobranchius furzeri fin biopsies

Project description:Here, we performed a longitudinal study of genome-wide gene expression in the short-lived killifish Nothobranchius furzeri (MZM-0410 strain) and correlated variations in transcript abundance at two time points during early adult life with age at death.

2020-06-24 | GSE150318 | GEO

Nothobranchius furzeri

Project description:Nothobranchius furzeri Genome sequencing

| PRJNA214908 | ENA

Nothobranchius furzeri

Project description:Diapause transcriptome of Nothobranchius furzeri

| PRJNA503701 | ENA

Nothobranchius furzeri

Project description:Turquoise killifish (Nothobranchius furzeri) gut microbiota

| PRJNA379271 | ENA

Nothobranchius furzeri strain:MZM-0403

Project description:Nothobranchius furzeri

| PRJNA33315 | ENA

Nothobranchius furzeri strain:GRZ

Project description:Nothobranchius furzeri strain:GRZ Epigenomics

| PRJNA259247 | ENA

RNA-seq of different tissues from wild-type and C/EBPα ΔuORF mutant African turquoise killifish Nothobranchius furzeri

Project description:The transcription factor CCAAT/enhancer binding protein alpha (C/EBPα) regulates cell differentiation, proliferation, and function in various tissues, including the liver, adipose tissue, skin, lung, and hematopoietic system. Studies in rats, mice, humans, and chickens have shown that CEBPA mRNA undergoes alternative translation initiation, producing three C/EBPα protein isoforms. Two of these isoforms act as full-length transcription factors with N-terminal transactivation domains and a C-terminal dimerization and DNA-binding domain. The third isoform is an N-terminally truncated variant, translated from a downstream AUG codon. It competes with full-length isoforms for DNA binding, thereby antagonizing their activity. Expression of the truncated C/EBPα isoform depends on the initial translation of a short upstream open reading frame (uORF) in CEBPA mRNA and subsequent re-initiation at a downstream AUG codon, a process stimulated by mTORC1 signaling. We have generated C/EBPα ΔuORF mutant Nothobranchius furzeri fish and demonstrated that this genetic modification significantly extended both the median and maximal lifespan and improved the healthspan of males. Comparative transcriptome analysis revealed an upregulation of genes and pathways that are associated with healthspan and lifespan regulation in other species.

2026-05-26 | E-MTAB-15325 | biostudies-arrayexpress

Nothobranchius furzeri

Project description:RNA-seq of the killifish Nothobranchius furzeri strain MZM-0410

| PRJNA294414 | ENA