Project description:Polycyclic aromatic hydrocarbons (PAHs) are a class of hundreds of structurally similar chemicals ubiquitously present in our environment. They are created during the incomplete combustion of organic materials, such as oil, wood, tobacco, and charbroiled meat. As such, human exposure to mixtures of PAHs can occur through consumption of PAH-containing foods and water, inhalation of polluted air, or dermal contact. Several PAHs have been classified as carcinogenic to humans or probably carcinogenic to humans by the International Agency for Research on Cancer. The mice in this study were exposed to a complex mixture of PAHs - coal tar. In the present study, we sought to determine the dose-dependent changes in gene expression upon oral exposure to this PAH mixture in the lung tissue. Adult male MutaTMMouse were exposed to three doses of the coal tar or vehicle control (olive oil) for 28 days and sacrificed three days after the final exposure.

2017-01-01 | GSE87690 | GEO

Short-term acidification promotes diverse iron acquisition and conservation mechanisms in upwelling-associated phytoplankton

Project description:Coastal upwelling regions are among the most productive marine ecosystems but may be threatened by amplified ocean acidification. Increased acidification is hypothesized to reduce iron bioavailability for phytoplankton thereby expanding iron limitation and impacting primary production. Here we show from community to molecular levels that phytoplankton in an upwelling region respond to short-term acidification exposure with iron uptake pathways and strategies that reduce cellular iron demand. A combined physiological and multi-omics approach was applied to trace metal clean incubations that introduced 1200 ppm CO2 for up to four days. Although variable, molecular-level responses indicate a prioritization of iron uptake pathways that are less hindered by acidification and reductions in iron utilization. Growth, nutrient uptake, and community compositions remained largely unaffected suggesting that these mechanisms may confer short-term resistance to acidification; however, we speculate that cellular iron demand is only temporarily satisfied, and longer-term acidification exposure without increased iron inputs may result in increased iron stress.

2023-11-14 | PXD038549 | Pride

marine upwelling 16S rDNA data

Project description:marine upwelling 16S rDNA data Raw sequence reads

| PRJNA639019 | ENA

marine upwelling 18S rDNA data

Project description:marine upwelling 18S rDNA data Raw sequence reads

| PRJNA628121 | ENA

Microbial diversity in the Benguela coastal upwelling system

Project description:Microbial diversity in the Benguela coastal upwelling system as derived from 16S rRNA sequencing and RNA Stable Isotope Probing (SIP)

| PRJEB20585 | ENA

Trophic ecology of Octopus vulgaris paralarvae along the Iberian Canary current eastern boundary upwelling system.

Project description: Not available

| S-EPMC10229560 | biostudies-literature