Project description:Mouse bone marrow derived macrophages were stimulated with L3 larvae of the helminth Heligmosomoides polygyrus (Hp) (500 L3 /1 mio cells) in the presence or absence of immune serum (1:50 v:v) from challenge-Hp-infected mice.
Project description:We used RNA-seq analyses and in vivo Heligmosomoides polygyrus (Hp) infection mouse models to identify roles for the CXCR5-expressing DCs in Th2 development.
Project description:In the present study we analyse the proteomic changes ocurring in murine macrophages RAW264.7 following stimulation with LPS and treatment with excretory/secretory products from Nippostrongylus brasiliensis or Heligmosomoides polygyrus.
