Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Single cell RNAseq of immune and stromal cells from clinically inflammed and non inflammed human lymph nodes

ABSTRACT: Single cell RNAseq of immune and stromal cells from clinically inflammed and non inflammed human lymph nodes

PROVIDER: PRJEB73512 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Single cell RNAseq of immune and stromal cells from clinically inflammed and non inflammed human lymph nodes

Project description:Because of their central role in inflammatory processes pathological alterations in lymph nodes can affect innate and adaptive immunity. However, interpretation of lymph node pathology in humans is hampered by the lack of a reference under homeostatic conditions and a limited understanding of the molecular processes that occur during inflammatory activation. Using a combination of confocal microscopy, flow cytometry, and single cell and spatial transcriptome analysis, our study provides an in-depth characterization of the immunoanatomy of clinically inflammed and non-inflamed human lymph nodes.

2025-03-31 | E-MTAB-13857 | biostudies-arrayexpress

Spatial transcriptomics from clinically non inflammed human lymph nodes

2025-03-31 | E-MTAB-13861 | biostudies-arrayexpress

Spatial transcriptomics from clinically non inflammed human lymph nodes

Project description:Spatial transcriptomics from clinically non inflammed human lymph nodes

| PRJEB73363 | ENA

scRNAseq of stromal cells isolated from mesenteric lymph nodes (MLN), peripheral lymph nodes (PLN) and mandibular lymph nodes (mandLN)

Project description:scRNAseq of stromal cells isolated from mesenteric lymph nodes (MLN), peripheral lymph nodes (PLN) and mandibular lymph nodes (mandLN)

2022-09-01 | E-MTAB-11644 | biostudies-arrayexpress

Different COVID-19 vaccines induce distinct reprogramming of stromal functions in draining lymph nodes

Project description:The non-leukocytic stromal cells of lymph nodes critically regulate immune responsiveness. However, the effects of different SARS-CoV-2 vaccines on stromal cell biology are unknown. We used single-cell transcriptomics to study early responses of stromal cells in draining lymph nodes after immunizing mice with clinically used COVID-19 vaccines, namely Spikevax®, Comirnaty®, Vaxzevria® and Nuvaxovid™. We found that vaccinations lead to robust transcriptomic changes, including vaccine-selective ones, in the different lymph node stromal cell populations priming the lymph node for the upcoming adaptive immune response.

2025-08-15 | GSE300959 | GEO

Gene expression signatures for murine stromal cells from tumor-draining lymph nodes

Project description:To determine the influence of primary tumors on pre-metastatic lymph nodes, we have employed whole genome microarray expression profiling as a discovery platform to identify gene signatures of stromal cells from tumor-draining lymph nodes, compared with normal lymph nodes. We subcutaneously inoculated C57BL/6 mice with the 4T1 mammary carcinoma. Two weeks later, tumor-draining lymph nodes were dissociated and stromal cells (CD45-) were sorted. Lymph nodes stromal cells from normal mice without tumor bearing were set as controls.

2018-04-18 | GSE113249 | GEO

scRNAseq of stromal cells isolated from mesenteric lymph nodes (MLN), peripheral lymph nodes (PLN) and mandibular lymph nodes (mandLN)

Project description:scRNAseq of stromal cells isolated from mesenteric lymph nodes (MLN), peripheral lymph nodes (PLN) and mandibular lymph nodes (mandLN)

| PRJEB52336 | ENA

Single cell RNAseq of immune and stromal cells from human lymph nodes

Project description:Single cell RNAseq of immune and stromal cells from human lymph nodes

| PRJEB52761 | ENA

Gene expression signatures for murine stromal cells from tumor-draining lymph nodes

Project description:Gene expression signatures for murine stromal cells from tumor-draining lymph nodes

| PRJNA450551 | ENA

Gene expression profiling of lymph node mesenchymal stromal cells in follicular lymphoma.

Project description:This study investigates the gene expression profiles of mesenchymal stromal cells derived from lymph nodes of patients with follicular lymphoma. Using microarray analysis, we identified differentially expressed genes involved in tumor progression and stromal cell differentiation.

2024-06-26 | GSE270555 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data