Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

IE Salmonella 2025

ABSTRACT: Irish Salmonella Isolates 2025

PROVIDER: PRJEB84468 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR14146400_1.fastq.gz	Fastqsanger.gz
	ERR14146400_2.fastq.gz	Fastqsanger.gz
	ERR14146403_1.fastq.gz	Fastqsanger.gz
	ERR14146403_2.fastq.gz	Fastqsanger.gz
	ERR14146424_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 268

Similar Datasets

Irish Shigella Isolates 2025

Project description:Irish Shigella Isolates 2025

| PRJEB89660 | ENA

IE Salmonella 2024

Project description:Isolates received to the Irish Salmonella Reference Laboratory (Human) in 2024

| PRJEB85329 | ENA

Irish Human L.monocytogenes isolates 2025

Project description:Irish Human L.monocytogenes isolates 2025

| PRJEB89661 | ENA

CPE/CPO isolates Ireland 2025

Project description:Isolates received by the Irish National CPE laboratory 2025

| PRJEB85322 | ENA

Transcription profiling of Salmonella enterica serovar Typhimurium definitive phage type 104 (DT104) isolates

Project description:Salmonella enterica serovar Typhimurium (S. Typhimurium) definitive phage type 104 (DT104) has caused significant morbidity and mortality in humans and animals for almost three decades. We have completed the full DNA sequence of one DT104 strain, NCTC13348 and show that the main differences between the genome of this isolate and the previously sequenced S. Typhimurium LT2 lie in integrated prophage elements and the Salmonella Genomic Island 1 encoding antibiotic resistance genes. Thirteen isolates of S. Typhimurium DT104 with different pulsed field gel electrophoresis (PFGE) profiles were analyzed by multi locus sequence typing (MLST), plasmid profiling, hybridization to a Pan-Salmonella DNA microarray and prophage-based multiplex PCR. All the isolates belonged to a single MLST type ST19. Microarray data demonstrated that the 13 DT104 isolates were remarkably conserved in gene content. The PFGE band-size differences in these isolates could be explained to a great extent by changes in prophage and plasmid content. Thus, here the nature of variation in different S. Typhimurium DT104 isolates is further defined at the genome level illustrating how this phage type is evolving over time.

2008-09-05 | E-MTAB-20 | biostudies-arrayexpress

A single missense mutation in hilD is responsible for further adaptation of a Salmonella Derby lineage to swine and reduced risk to human health

Project description:Salmonella enterica variants exhibit diverse host adaptation, outcome of infection, and associated risk to humans. Analysis of 6,335 Salmonella isolates recovered from integrated human-animal surveillance in Emilia Romagna region, Northern Italy, (human population ca 4,500,000), from 2012 to 2017 showed that Salmonella enterica serovar Derby constitutes a swine associated serovar in this epidemiological context while representing also a significant causative agent of human infections. Comparison of the distribution of subtypes of Salmonella Derby from human and swine identified isolates with a distinct PFGE profile that were significantly less isolated in human infections than in swine infections compared to all other subtypes. Here we show that isolates with this PFGE profile form a distinct phylogenetic sub-clade within Salmonella Derby and exhibit a marked reduction in invasion and replication in human epithelial cells but a relatively small reduction in swine epithelial cells, in line with the epidemiological evidence. A single missense mutation in hilD, that encodes the master-regulator of the Salmonella Pathogenicity Island 1 (SPI-1), was identified in this lineage of Salmonella Derby. Since SPI-1 encodes for a primary system of Salmonella invasion into epithelial cells, we investigated the role of the observed mutation in detail. We demonstrated that the missense mutation results in a loss of function of HilD that accounts for the reduced invasion and replication in human epithelial cells while showing a relatively small impact on the interaction with swine cells. This finding is suggestive of a mechanism of invasion alternative to SPI-1 in the Salmonella-swine combination

2020-12-16 | GSE142220 | GEO

Transcriptomic comparison of chlorhexidine tolerant and sensitive Salmonella Typhimurium

Project description:Transcriptional profiles of a chlorhexidine tolerant Salmonella Typhimurium were compared to its, chlorhexidine sensitive, isogenic progenitor isolate. RNA was extracted from mid-log phase cells from both isolates, without chlorhexidine exposure and following exposure to 1 µg/ ml of chlorhexidine for 30 minutes. Transcriptional profiles of the tolerant isolate were compared to the sensitive isolate, with and without chlorhexidine exposure.

2015-06-06 | GSE59566 | GEO

Salmonella enterica subsp. enterica

Project description:Salmonella from the Irish pre-harvest pork chain

| PRJNA438944 | ENA

Transcriptomic comparison of chlorhexidine tolerant and sensitive Salmonella Typhimurium

2015-06-06 | E-GEOD-59566 | biostudies-arrayexpress

Grazing Microbiome 2025

Project description:Grazing Microbiome 2025

| PRJNA1271444 | ENA