Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

GRANTA-519 Nanopore sequencing: Technical Assessment of Long-Read Nanopore Whole-Genome Sequencing for Detecting Large Chromosomal Alterations in Mantle Cell Lymphoma

ABSTRACT: GRANTA-519 Nanopore sequencing

PROVIDER: PRJEB89774 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR15004792.fastq.gz	Fastqsanger.gz
	ERR15004793.fastq.gz	Fastqsanger.gz

Items per page:

1 - 2 of 2

Similar Datasets

Next Generation Sequencing of Mantle cell lymphoma Granta-519 Transcriptomes

Project description:Purpose: The goal of this study is to get a deeper insight of whole transcriptome changes and of signaling pathways involved in eliciting the DPN-mediated effects on Granta-519 tumor progression in vivo. Methods: Mantle cell lymphoma cell line Granta-519 cells were grafted to male NSG mice, followed by treated with ESR2 selective agonist DPN or vehicle. When tumor size reached around 1300 mm3, RNA was extracted with RNeasy Plus Mini Kit (Qiagen) for sequencing. Results: ESR2 selective agonist DPN could inhibit cell adhesion, EMT and angiogenesis in vivo which likely involves regulation of VEGFA, FOS, FOSB, CXCR4, MALAT1 and NEAT1. Conclusions: Our study represents the detailed analysis of Granta-519 transcriptomes in vivo experiment after DPN treatment, with biologic replicates, generated by RNA-seq technology.

2022-07-01 | GSE190600 | GEO

PB2386: ASSESSMENT OF NANOPORE LONG-READ WHOLE-GENOME SEQUENCING FOR THE DETECTION OF LARGE CHROMOSOMAL STRUCTURAL VARIANTS IN MANTLE CELL LYMPHOMA

Project description: Not available

| S-EPMC10429199 | biostudies-literature

Next Generation Sequencing of Mantle cell lymphoma Granta-519 Transcriptomes

Project description:Next Generation Sequencing of Mantle cell lymphoma Granta-519 Transcriptomes

| PRJNA787626 | ENA

Detecting Large Chromosomal Modifications Using Short Read Data From Genotyping-by-Sequencing.

Project description: Not available

| S-EPMC6771380 | biostudies-literature

Gene expression analysis of JVM-2 and Granta-519 after CCDC50 gene modulation

Project description:Microarray-based gene expression analysis identified genes differentially expressed in JVM-2 and Granta-519 after CCDC50 gene modulation.

2010-06-03 | GSE16435 | GEO

The Precise Basecalling of Short-Read Nanopore Sequencing.

Project description: Not available

| S-EPMC11429927 | biostudies-literature

Engineering psychrophilic polymerase for nanopore long-read sequencing.

Project description: Not available

| S-EPMC11246872 | biostudies-literature

MiR-16 and miR-519 suppress tumor cell proliferation in meningiomas via HuR inhibition

Project description:We investigated the relative expression levels of these miRs in a series of meningioma and normal meningeal tissues. The effects of miR-16 and miR-519 on cell growth and transcriptome were assessed in vitro using two human cell lines (Ben-Men-1 and IOMM-Lee). Both miR-16 and miR-519 were significantly downregulated in meningioma compared with normal meningeal tissue. Overexpression of either miR in IOMM-Lee and Ben-Men-1 cells significantly reduced cell growth. The transfection of miR-16 and miR-519 significantly downregulated HuR mRNA, and genes involved in various functions such as pre-replicative complex, mitotic recombination, S phase and M phase of cell cycle, and upregulated genes implicated in cell junction, and positive regulation of cell death. Cell-cycle-related genes associated cluster included HuR mRNA (ELAVL1), and was highly enriched with HuR gene targets.

2023-07-03 | GSE98848 | GEO

Saccharum spontaneum cultivar:US 78-519

Project description:Saccharum spontaneum US 78-519 Resequencing

| PRJNA1228880 | ENA

Long-read Oxford nanopore sequencing reveals a de novo case of complex chromosomal rearrangement involving chromosomes 2, 7, and 13.

Project description: Not available

| S-EPMC9482406 | biostudies-literature