Project description:Exposure to high-dose radiation causes life-threatening serious intestinal damage. Histological analysis is the most accurate method for judging the extent of intestinal damage after death. However, it is difficult to predict the extent of intestinal damage to body samples. Here we focused on extracellular microRNAs (miRNAs) released from cells and investigated miRNA species that increased or decreased in serum and feces using a radiation-induced intestinal injury mouse model. A peak of small RNA of 25–200 nucleotides was detected in mouse serum and feces 72 h after radiation exposure, and miRNA presence in serum and feces was inferred. MiRNAs expressed in the small intestine and were increased by more than 2.0-fold in serum or feces following a 10 Gy radiation exposure were detected by microarray analysis and were 4 in serum and 19 in feces. In this study, miR-375-3p, detected in serum and feces, was identified as the strongest candidate for a high-dose radiation biomarker in serum and/or feces using a radiation-induced intestinal injury model.

2023-12-15 | GSE247876 | GEO

several metagenomic assembled genomes (MAGs) from sediments

Project description:several metagenomic assembled genomes (MAGs) from sediments

| PRJNA957236 | ENA

Feces 16S rRNA seq of mice treated by AZ1 with 2.5% DSS or H2O

Project description:Feces 16s rRNA seq experiments is required to demonstrate the AZ1 doesn’t impact the intestinal microbiota.

2020-02-14 | GSE143003 | GEO

Metagenomic assembled genomes from M. arvalis, B. taurus and O. aries feces

Project description:Metagenomic assembled genomes from M. arvalis, B. taurus and O. aries derived from grassland

| PRJEB88003 | ENA

Intestinal tumor expression data from Apcmin/+ mice gavaged by feces from healthy controls or colorectal cancer patients

Project description:Colorectal cancer (CRC) is closely related to gut dysbiosis. We investigated the effects of imbalanced gut microbiota on the progression of intestinal adenoma in Apcmin/+ mice model using fecal microbiota transplantation (FMT). Administration of feces from CRC patients increased tumor proliferation and decreased apoptosis in tumor cells. Abnormal expression of genes related to Wnt-protein binding and lipid metabolic process was observed.

2019-09-16 | GSE136682 | GEO

Schlöppnerbrunnen omics: 13 metagenome-assembled genomes

Project description:The Schlöppnerbrunnen fens are a long studied model system for peatland/wetland research. This BioProject includes metagenome-assembled genomes binned from PRJNA412436.

| PRJEB24926 | ENA

Metagenomic assembled genomes from three ice covered boreal lakes

Project description:Metagenomic assembled genomes from three ice covered boreal lakes.

| PRJNA417934 | ENA