Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: the effects of chlorogenic acid on mice (detecte fecal miRNA)

PROVIDER: PRJNA1037327 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR26808200.fastq.gz	Fastqsanger.gz
	SRR26808201.fastq.gz	Fastqsanger.gz
	SRR26808202.fastq.gz	Fastqsanger.gz
	SRR26808203.fastq.gz	Fastqsanger.gz
	SRR26808204.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 14

Similar Datasets

Project description:the effects of chlorogenic acid on mice

| PRJNA1035224 | ENA

Project description:Chlorogenic acid improves obesity

| PRJNA1306754 | ENA

Project description:chlorogenic acid and caffeic acid-fan

| PRJNA752260 | ENA

RNA-sequencing data of mouse macrophages exposed to polyphenols or polyphenol-amino acid adducts

Project description:We show here the transcriptional response in mouse macrophages stimulated with LPS alone, LPS together with caffeic acid or chlorogenic acid, or the corresponding polyphenol-cystiene adducts

2022-06-24 | GSE206519 | GEO

Chicory: cutting the effects and the effectors for a functional food

Project description:Whole chicory flour (Chic) and three compounds of chicory roots: fructose (Fru), chlorogenic acids (CGA) and sesquiterpene lactones (STL) were separately analyzed for their health effects in mice. A whole transcriptomic analysis was conducted using Agilent DNA microarrays to investigate their nutrigenomic effects.

2022-03-24 | GSE190056 | GEO

Project description:Effects of chlorogenic acid on liver transcriptome in Mauremys mutica

| PRJNA1213983 | ENA

Project description:Chlorogenic acid transcriptome of sweetpotato leaves

| PRJNA1016354 | ENA

Effect of morphine treatment on microbiome in the context of microbial transplant.

Project description:Morphine causes microbial dysbiosis. In this study we focused on restoration of native microbiota in morphine treated mice and looked at the extent of restoration and immunological consequences of this restoration. Fecal transplant has been successfully used clinically, especially for treating C. difficile infection2528. With our expanding knowledge of the central role of microbiome in maintenance of host immune homeostasis17, fecal transplant is gaining importance as a therapy for indications resulting from microbial dysbiosis. There is a major difference between fecal transplant being used for the treatment of C. difficile infection and the conditions described in our studies. The former strategy is based on the argument that microbial dysbiosis caused by disproportionate overgrowth of a pathobiont can be out-competed by re-introducing the missing flora by way of a normal microbiome transplant. This strategy is independent of host factors and systemic effects on the microbial composition. Here, we show that microbial dysbiosis caused due to morphine can be reversed by transplantation of microbiota from the placebo-treated animals.

2016-06-01 | E-MTAB-3723 | biostudies-arrayexpress

16SrRNA analysis from wildtype mice that were either fed or not with low protein diets for 4 weeks

Project description:We found that low protein diet consumption resulted in decrease in the percentage of normal Paneth cell population in wild type mice, indicating that low protein diet could negatively affect Paneth cell function. We performed fecal microbiota composition profiling. Male mice were used at 4-5 weeks of age. Fecal samples were collected for microbiome analysis.

2023-07-02 | E-MTAB-11277 | biostudies-arrayexpress

The regulatory mechanism of chlorogenic acid on fatty acid metabolism in human embryonic stem cells

Project description:Chlorogenic acid (CGA) is a crucial bioactive dietary polyphenol found in plants and serves as the primary ingredient in numerous traditional Chinese medicine preparations. Due to its beneficial impact on treating metabolic syndrome, it has garnered significant attention in medical research. Previous studies have demonstrated that chlorogenic acid possesses antioxidative, antibacterial, antiviral, anti-tumor, lipid-lowering, glucose-lowering, and immunomodulatory properties, indicating its potential role in regulating metabolism. Human embryonic stem cells (hESCs) exhibit self-renewal and multi-directional differentiation capabilities. Any element within the culture system can alter the microenvironment and influence hESC metabolism. Therefore, hESCs provide a valuable and high-throughput model for investigating CGA's regulatory mechanism on metabolism in vitro. While previous studies have explored CGA's important regulatory role in human metabolism, its specific impact on hESCs metabolism remains undisclosed. Metabolites of hESCs are critical targets for enhancing stem cell function regulation. Prior research has emphasized the essential nature of de novo synthesis and β-oxidation of fatty acids for regulating hESCs; however, CGA's roles and mechanisms in regulating fatty acid metabolism within hESCs remain unelucidated. This study utilizes transcriptome analysis combined with epigenetics to investigate CGA's regulation of fatty acid metabolism within hESCs while analyzing the molecular mechanisms involved—providing a theoretical foundation for future regulation of HESC metabolism by CGA and offering potential optimizations for hESCs culture systems.

2025-01-20 | GSE268203 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data