Project description:To elucidate the mechanism by which Arctium lappa L. polysaccharide (ALP) promotes epidermal stem cell (EpSC) proliferation, we performed RNA sequencing on EpSCs from mice that were treated with either 30 μg/mL ALP or a vehicle control for 48 hours. This approach provided a comprehensive view of the ALP-regulated transcriptome profile.
Project description:The title compound {systematic name: (3R-trans)-4-[(3,4-dimethoxy-phen-yl)meth-yl]-3-[(4-hydr-oxy-3-methoxy-phen-yl)meth-yl]-4,5-dihydrofuran-2(3H)-one}, C(21)H(24)O(6), has a dibenz-yl-butyrolactone skeleton. The two aromatic rings are inclined at a dihedral angle of 68.75 (7)° with respect to each other. The lactone ring adopts an envelope conformation. A series of O-H⋯O and C-H⋯O hydrogen bonds contribute to the stabilization of the crystal packing. The absolute configuration was assigned on the basis of the published literature.