Project description:This is the first report evaluating the use of fluorescent imaging to determine the pharmacokinetics, lymphatic uptake, and bioavailability of a near-infrared dye-labeled antibody conjugate. Model is encoded by Matthew Roberts and submitted to BioModels by Krishna Tiwari.
Project description:To clarify the effects of near-infrared radiation, we assessed DNA microarray after water-filtered broad-spectrum near-infrared (1100-1800 nm together with a water-filter that excludes wavelengths 1400-1500 nm) irradiation. We performed 5 rounds of near-infrared irradiation (at 10 J âcm2) using 2 sets of transparent polycarbonate plates, one to block UV and the other to block both UV and near-infrared.
Project description:To clarify the effects of near-infrared radiation, we assessed DNA microarray after water-filtered near-infrared (1100-1800 nm together with a water-filter that excludes wavelengths 1400-1500 nm) irradiation.
Project description:To clarify the effects of near-infrared radiation, we assessed DNA microarray after water-filtered broad-spectrum near-infrared (1100-1800 nm together with a water-filter that excludes wavelengths 1400-1500 nm) irradiation.
Project description:Primary objectives: - Evaluate tumour detection sensitivity and specificity with the following image enhancement modalities:
- 1 ‘narrow-band imaging’, 2 ‘autofluorescent imaging’, 3 ‘near-infrared indocyanin green imaging’, 4 ‘5-aminolevulinic acid fluorescent imaging’, 5 ‘three-dimensional imaging’ and 6 ‘spray-dye chromoendoscopy’ compared to conventional white light laparoscopy in patients with peritoneal carcinomatosis in order to achieve best tumour detection.
Primary endpoints: -Evaluate tumour detection sensitivity and specificity with the following image enhancement modalities:
1 ‘narrow-band imaging’, 2 ‘autofluorescent imaging’, 3 ‘near-infrared indocyanin green imaging’, 4 ‘5-aminolevulinic acid fluorescent imaging’, 5 ‘three-dimensional imaging’ and 6 ‘spray-dye chromoendoscopy’ compared to conventional white light laparoscopy in patients with peritoneal carcinomatosis in order to achieve best tumour detection.
Project description:Gold nanorods mediated photothermal therapy represents a promising technique for cancer treatment, utilizing GNRs in conjunction with near-infrared laser irradiation to convert energy into heat. In the present study, we employed PTT to induce apoptosis in pancreatic cancer cells and investigated its underlying mechanisms through quantitative proteomics analysis.
Project description:Interventions: To assess the blood flow at anastomotic site by comparing a direct vision with that under near infrared light after intravenous infusion of indocyanine green.
Primary outcome(s): Is it effective or not to assess blood flow at anastomotic site by indocyanine green fluorescent imaging?
Study Design: Single arm Non-randomized
Project description:Interventions: Administration of either Indocyanine Green (ICG) or 5-aminolevulinic acid (5-ALA) preoperatively
Primary outcome(s): To evaluate the sensitivity and specificity of Narrow Band Imaging, Near-infrared Indocyanin Green Imaging, 5-ALA fluorescent imaging and Indigo Carmine Blue Spray Dye Chromoendoscopy in the detection of malignant lesions.
Study Design: N/A , unknown, Other
