Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Multi-hosts distribution of Rhodococcus equi (Prescotella equi) strains

PROVIDER: PRJNA1065651 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR27608130_1.fastq.gz	Fastqsanger.gz
	SRR27608130_2.fastq.gz	Fastqsanger.gz
	SRR27608131_1.fastq.gz	Fastqsanger.gz
	SRR27608131_2.fastq.gz	Fastqsanger.gz
	SRR27608132_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 76

Similar Datasets

Project description:Rhodococcus equi

| PRJNA857424 | ENA

Prescottella equi

Project description:Rhodococcus equi overview

| PRJNA37631 | ENA

Prescottella equi

Project description:Antimicrobial-resistant Rhodococcus equi (Prescottella equi)

| PRJDB15571 | ENA

RNA-Seq identifies differential gene expression associated with risk-genotype for Rhodococcus equi pneumonia in horses

Project description:Rhodococcus equi is an intracellular bacterium that affects young foals and immuno-compromised individuals causing severe pneumonia. Currently, the genetic mechanisms which confer susceptibility and or resistance to R. equi are not fully understood. Previously, using a SNP-based genome-wide association study, we identified a region on equine chromosome 26 associated with clinical pneumonia. To better characterize this region and understand the relationship of the SNPs associated with disease, we performed RNA-Seq on 12 horses representing the 3 allelic states of the SNP identified. Differential expression analyses identified differentially expressed genes in the innate immune response pathway when comparing homozygous A allele horses with the AB and BB horses. Isoform analyses of the RNA-Seq data predicted multiple transcripts with evidence of differential expression to exist at the TRPM2 locus. This finding is consistent with previously demonstrated work in human cell lines in which isoform specific expression of TRPM2 was critical to cell viability. This work demonstrates that SNPs in TRPM2 are associated with differences in gene expression, suggesting that modulation of expression of this innate immune gene contributes to susceptibility to R. equi pneumonia.

2016-05-25 | GSE81858 | GEO

Prescottella equi

Project description:Rhodococcus equi Raw sequence reads

| PRJNA592075 | ENA

Prescottella equi

Project description:Genome sequencing of Rhodococcus equi

| PRJDB12562 | ENA

Prescottella equi

Project description:Genome sequencing of Rhodococcus equi

| PRJDB10801 | ENA

Rhodococcus equi F6

Project description:Rhodococcus equi F6 Raw sequence reads

| PRJNA526377 | ENA

Project description:Four Rhodococcus equi isolated from patients

| PRJNA773582 | ENA

Comprehensive proteomics for Discovery vaccine candidates against Streptococcus equi Infections

Project description:Streptococcus equi subspecies equi (S. equi) is a major pathogen which cause strangles, a highly contagious respiratory infection, in horses and other equines. In this study, we purified the extracellular vesicles (EVs) of S. equi ATCC 39506 and evaluated them as vaccine candidates against S. equi infections in mice. Through immunization in an animal model and immunoprecipitation-mass spectrometry, we evaluated EV as vaccine candidates against S. equi infections and identified novel immunogenic proteins.

2021-08-06 | PXD025527 | Pride

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data