Project description:As marine invertebrates, scallops lack adaptive immunity and employ innate immunity as the front line and almost the solo defense mechanism to protect them against invaders. Accumulating research achievements demonstrated that exosomes could act as innate immune effectors that contribute to host defense mechanism. To better understand the immune functions of exosomes in Chlamys farreri, miRNA profiles of hemocytes from scallops injected with PBS, with normal exosomes and LPS stimulating exosomes, respectively, were generated by deep sequencing, in triplicate.
Project description:As marine invertebrates, scallops lack adaptive immunity and employ innate immunity as the front line and almost the solo defense mechanism to protect them against invaders. Accumulating research achievements demonstrated that exosomes could act as innate immune effectors that contribute to host defense mechanism. To better understand the immune functions of exosomes in Chlamys farreri, mRNA profiles of hemocytes from scallops injected with PBS, with normal exosomes and LPS stimulating exosomes, respectively, were generated by deep sequencing, in triplicate.
Project description:Exosomes are innate immune effectors that deliver biologically active substances between cells to fight pathogenic infections. As marine invertebrates, scallops rely primarily on innate immunity to protect against external stimuli. In order to better explore the role of exosomes in innate immunomodulation mediated by exosomes in Chlamys farreri, DIA proteomics quantitative analysis was performed on exosomes in serum of untreated and LPS-treated Chlamys farreri, with three replicates in each group. The scallops were randomly divided into control group (CFEXO) and LPS stimulation group (CFEXO_LPS).
2025-03-31 | PXD062432 |
Project description:gut microbiota of scallop (Chlamys farreri) under Benzo(a)pyrene exposure
