Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Single Cell sequencing analysis of Mouse Bladder Tumor Samples

ABSTRACT: Single Cell sequencing analysis of Mouse Bladder Tumor Samples

PROVIDER: PRJNA1081310 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR28114553_1.fastq.gz	Fastqsanger.gz
	SRR28114553_2.fastq.gz	Fastqsanger.gz
	SRR28114554_1.fastq.gz	Fastqsanger.gz
	SRR28114554_2.fastq.gz	Fastqsanger.gz
	SRR28114555_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 8

Similar Datasets

Single Cell sequencing analysis of Mouse Bladder Tumor Samples

Project description:Single-cell RNA sequencing analysis identifies acute changes in the tumor microenvironment induced by interferon α gene therapy in a murine model of bladder cancer.

2025-02-26 | GSE259337 | GEO

Bladder tumor sequencing

Project description:Prospective sequencing of a patient's bladder tumor

2016-12-31 | GSE81201 | GEO

Single-cell RNA sequencing of bladder Ewing sarcoma

Project description:Bladder Ewing sarcoma/primitive neuroectodermal tumor (bladder ES/PNET) is a rare and highly malignant tumor associated with a poor prognosis, yet its underlying mechanisms remain poorly understood. This study employed a combination of single-cell RNA sequencing (scRNA-seq) analyses to delve into the pathogenesis of bladder ES/PNET. The investigation revealed the presence of specialized types of epithelial cells (referred to as bladder ES-Epi) and mast cells (referred to as bladder ES-Mast) within bladder ES/PNET in comparison to urothelial carcinoma. Notably, TNFRSF12A exhibited significant upregulation in bladder ES/PNET. Furthermore, mast cells possessed the ability to activate epithelial cells through the TNFSF12-TNFRSF12A ligand-receptor signaling pattern. This activation mechanism appears to contribute to the progression of bladder ES/PNET.

2024-09-05 | GSE250523 | GEO

Transcriptomic Characterization of Local Invasion in Human Bladder Cancer by Single Cell RNA Sequencing

Project description:Investigating intra-tumor heterogeneity of bladder cancer has been largely based on conventional pathological staging and bulk samples sequencing for analyzed multiple spatially separated regions within one tumor. However, it still lack a comprehensive understanding for this question at single cell resolution.

2021-11-11 | GSE135337 | GEO

Single cell RNA seq of mouse bladder and bladder assembloids

Project description:To investigate whether the bladder assembloids recapitulate cell compositions, in addition to the gene expression patterns of each cell type in the adult bladder, we performed single-cell RNA-seq of bladder assembloids and mouse adult bladders, and compared the transcriptional profiles between them at the single-cell level.

2020-09-27 | GSE141348 | GEO

Single cell RNA seq of mouse bladder and bladder assembloids

Project description:Single cell RNA seq of mouse bladder and bladder assembloids

| PRJNA593201 | ENA

Human bladder cancer and colon cancer quatitative MS/MS

Project description:We analyzed a set of 40 independently collected tumor tissue/control samples using a label-free quantitation single pass LC-MS/MS approach. In this set, 10 samples originated from a colon tumor (i.e. AC) and 10 from control non-malignant tissue samples (NCA), as well as 10 from BC samples and 10 from control bladder tissue (NCB) samples.

2016-12-14 | PXD004249 | Pride

Transcriptional profiling of tumor-associated blood vessels in invasive bladder cancer

Project description:Tumor-associated blood vessels differ from normal vessels at the morphological and molecular level. Proteins that are only present on tumor vessels may serve as biomarkers and as therapeutic targets for inhibition of angiogenesis in cancer. Comparing the transcriptional profiles of blood vascular endothelium from human invasive bladder cancer and from normal bladder tissue, we found several markers that could serve as novel biomarkers or therapeutic targets. In this dataset, we include the expression data obtained from laser capture microdissected (LCM) vessels isolated from tumor and bladder normal tissue. 10 samples were analyzed. We compared expression of tumor associated blood vessels with expression of vessels in the normal bladder tissue using Genespring GX 12.

2013-03-08 | E-GEOD-41614 | biostudies-arrayexpress

Single-cell dissection of multifocal bladder cancer reveals malignant and immune cells variation between primary and recurrence tumor lesions

Project description:Bladder carcinoma (BLCA) is characterized by a high rate of post-surgery relapse and multifocality, with multifocal tumors carrying a 40% higher risk of recurrence compared to single tumors. Recurrence is a major contributor to bladder cancer-specific mortality. However, understanding interregional or intraregional malignant heterogeneity and cellular communication within the primary and recurrence tumor microenvironment (TME) remains a significant challenge. Here, we employed single-cell RNA sequencing (scRNA-seq) to analyze separate tumor lesions from five multifocal bladder cancer patients (comprising three primary tumors and two recurrence tumors).

2024-11-15 | GSE277524 | GEO

Human bladder cancer and colon cancer quatitative MS/MS

| MSV000082886 | MassIVE