Project description:Study comparing the effects on APAP, high fat diet and gut microbiome composition on urine, serum and colonic content/fecal metabolomes from male C57BL6/J mice. Microbiome conditions include mice that were germ-free (GF), fecal microbiota colonized (convention mouse FMT) and conventional mice with gentamicin or vancomycin shifted gut microbiomes. LC-MS/MS data acquisition was completed in positive and/or negative ionization mode.
Project description:Investigating alterations the intestinal microbiome in a diet induced obesity (DIO) rat model after fecal transplant from rats, which underwent Roux-Y-Gastric-Bypass surgery (RYGB). The microbiomes of the RYGB-donor rats, the DIO rats, and DIO rats after receiving the fecal transplant from the RYGB rats. As controls lean rats as well as lean, RYGB and DIO rats after antibiotics treatment were used.
