Project description:Eurasian common shrews (Sorex araneus) maintain exceptionally high metabolic rates year-round, posing a significant energetic challenge during winter when food availability declines. To investigate seasonal metabolic regulation, we performed proteomic profiling of liver tissue—central to energy homeostasis—across seasons, using a bottom-up/shotgun DDA LC-MSMS proteomics analytical strategy. This approach reveals molecular adaptations that support metabolic resilience and highlights key regulatory shifts in response to environmental stress. The files and search results are labelled as: Liver_<YEAR>_<MONTH>_G_Juvanile/Adult_Mouse#1-5 Example: “Liver_2020_07_G_J2” is a liver sample collected in 2020 month 07 from juvenile mouse #2 Liver_2020_07_G_J1-5: summer 2020 Liver_2020_11_G_J1-4: fall 2020 Liver_2021_04_G_A1-5: spring 2021 Liver_2021_06_G_A1-5: summer 2021 By exploring these mechanisms, we offer novel insights into the interplay between metabolism, size, and longevity, shedding light on both the wintering strategy of the common shrew and broader mammalian physiology.
2025-10-31 | PXD068559 | Pride
Project description:Saint John Harbour Macroalgal & Phytoplankton Monitoring Project (2020-2021)
Project description:Single-cell RNA-sequencing was performed on the tumor microenvironment of the glioblastomas isolated from PDOX models (Golebiewska et al., Acta Neuropathologica, 2020; Oudin et al., STAR Protocols 2021). Sample names correspond to PDOX models. Normal mouse brain was used as a contol. One PDOX model was treated with temolozomide (P3TMZ).
2023-03-07 | GSE226468 | GEO
Project description:Clear Lake Cyanobacteria 2020-2021
Project description:In this project, we developed a data resource based on the German winter oilseed rape cultivar Express 617. Plants were grown under controlled environmental conditions in the container-based system of the IPK PhenoSphere in 2020-2021. The dataset comprises gene expression data generated by RNA sequencing of different seed tissues across five stages of seed development, spanning early embryo/seed development, seed filling, and seed maturation. In the first stage (pre-storage), whole seeds were analysed. In the later four stages, developing seeds were dissected into four organs/tissues (SC = seed coat, IC = inner cotyledon, OC = outer cotyledon, and RA = radicle). This dataset (mRNA sequencing) is part of a series of multi-omics data generated in the frame of the AVATARS project.