Ontology highlight
ABSTRACT:
PROVIDER: PRJNA1091597 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:Eurasian common shrews (Sorex araneus) maintain exceptionally high metabolic rates year-round, posing a significant energetic challenge during winter when food availability declines. To investigate seasonal metabolic regulation, we performed proteomic profiling of liver tissue—central to energy homeostasis—across seasons, using a bottom-up/shotgun DDA LC-MSMS proteomics analytical strategy. This approach reveals molecular adaptations that support metabolic resilience and highlights key regulatory shifts in response to environmental stress. The files and search results are labelled as: Liver_<YEAR>_<MONTH>_G_Juvanile/Adult_Mouse#1-5 Example: “Liver_2020_07_G_J2” is a liver sample collected in 2020 month 07 from juvenile mouse #2 Liver_2020_07_G_J1-5: summer 2020 Liver_2020_11_G_J1-4: fall 2020 Liver_2021_04_G_A1-5: spring 2021 Liver_2021_06_G_A1-5: summer 2021 By exploring these mechanisms, we offer novel insights into the interplay between metabolism, size, and longevity, shedding light on both the wintering strategy of the common shrew and broader mammalian physiology.
2025-10-31 | PXD068559 | Pride
Project description:Changes in sensory gene expression may underly seasonal changes in behavior. To accompany other research on seasonal changes in coloration and behavior in the seasonally plastic common buckeye butterfly Junonia coenia, we examined how gene expression in eyes differs between wild butterflies caught in summer and fall. We collected animals in 2019, 2020, and 2021 in the central United States. The samples consisted of three males and three females from each season: Summer (June/July) and Fall (late September/October) that had wing colors appropriate for previously described seasonal morphs (i.e. light in summer and dark in fall). We dissected eye tissue from butterfly heads and purified RNA prior to sending samples to Novogene for cDNA Library prep and RNA-Sequencing. We used DESeq2 for subsequent analysis. We found gene expression correlated to sex, season, and interactions between sex and season. Eye tissues from dark fall animals and light summer animals exhibit different patterns of expression in many genes including visual system development genes, pigmentation genes, and clock genes. This change in gene expression accompanies changes in basking behavior and wing color and indicates that J. coenia undergoes changes to its visual system depending on the seasonal environment.
2025-10-24 | E-MTAB-15925 | biostudies-arrayexpress
Project description:Single-cell RNA-sequencing was performed on the tumor microenvironment of the glioblastomas isolated from PDOX models (Golebiewska et al., Acta Neuropathologica, 2020; Oudin et al., STAR Protocols 2021). Sample names correspond to PDOX models. Normal mouse brain was used as a contol. One PDOX model was treated with temolozomide (P3TMZ).
2023-03-07 | GSE226468 | GEO
Project description:EFSA Confirm 2021 (2020 data)
| PRJEB70301 | ENA