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Transcriptomic changes in SUDHL6 cells upon treatment with S63845 in the presence or abscence of active caspases

ABSTRACT: Transcriptomic changes in SUDHL6 cells upon treatment with S63845 in the presence or abscence of active caspases

PROVIDER: PRJNA1096049 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR28550003_1.fastq.gz	Fastqsanger.gz
	SRR28550003_2.fastq.gz	Fastqsanger.gz
	SRR28550004_1.fastq.gz	Fastqsanger.gz
	SRR28550004_2.fastq.gz	Fastqsanger.gz
	SRR28550005_1.fastq.gz	Fastqsanger.gz

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Transcriptomic changes in SUDHL6 cells upon treatment with S63845 in the presence or abscence of active caspases

Project description:We identified a novel form of caspase-independent cell death (CICD) induced by BH3-mimetics. To characterize the transcriptional changes during CICD and compare these to apoptotic changes, we performed RNA Seq analysis on SUDHL6 lymphoma cells treated with the MCL1 inhibitor S63845 in the presence or abscence of the broad spectrum caspase inhibitor zVAD.fmk.

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