Project description:To explore the possible role of Nsd2 in kidney cancer, the gene expression profile of kisney tissues from KMN (Ksp-Cre; Myc OE/+; Nsd2 OE/+) and littermate KM (Ksp-Cre; Myc OE/+) mice was examined by RNA sequencing(RNA-Seq).
Project description:This dataset comprises analysis data obtained from the kidney tissues of six mice with sepsis induced by intraperitoneal injection of lipopolysaccharide (LPS) (n=6), as well as six mice with kidney injury secondary to sepsis (n=6). The kidney tissues were harvested 24 hours post the establishment of the mouse models, and subsequent sequencing was conducted utilizing mass spectrometry technology.
Project description:Rhodamin 123 is a dye which can be used to detect the activity of ABC transporters. We observed that after staining of KM-H2 Hodgkin lymphoma cells with Rhodamin 123, part of the cells rapidly eliminated the dye, while another part of the cells retained the dye for a longer time. We compared the transcriptome of KM-H2 Hodgkin lymphoma cells with high Rhodamin 123 efflux capacity and KM-H2 cells with low Rhodamin 123 efflux capacity.
Project description:Kidney tissues were collected from mice 2 weeks after BDL and sham operations. Membrane fractions of the kidney were prepared. After sample preparation, the proteome analysis was performed.
Project description:The transcriptional profile of kidney organoid-based tissues resembled the gene signature observed in human kidney transplant rejection when transplanted into mice reconstituted with an allogeneic immune system.