Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Multidrug-resistant bacteria from wastewater in Spain

PROVIDER: PRJNA1113845 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	SRR30160830_1.fastq.gz	Fastqsanger.gz
	SRR30160830_2.fastq.gz	Fastqsanger.gz
	SRR30160831_1.fastq.gz	Fastqsanger.gz
	SRR30160831_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 25

Similar Datasets

Antibiotic Resistance Profile and Genomic Characteristics of Multidrug-Resistant Bacteria from the Sludge of a Pharmaceutical Wastewater Treatment Plant

Project description:Incomplete antibiotic removal in pharmaceutical wastewater treatment plants (PWWTPs) could lead to the development and spread of antibiotic-resistant bacteria (ARBs) and genes (ARGs) in the environment, posing a growing public health threat. In this study, two multiantibiotic-resistant bacteria, Ochrobactrum intermedium (N1) and Stenotrophomonas acidaminiphila (N2), were isolated from the sludge of a PWWTP in Guangzhou, China. The N1 strain was highly resistant to ampicillin, cefazolin, chloramphenicol, tetracycline, and norfloxacin, while the N2 strain exhibited high resistance to ampicillin, chloramphenicol, and cefazolin. Whole-genome sequencing revealed that N1 and N2 had genome sizes of 0.52 Mb and 0.37 Mb, respectively, and harbored 33 and 24 ARGs, respectively. The main resistance mechanism in the identified ARGs included efflux pumps, enzymatic degradation, and target bypass, with the N1 strain possessing more multidrug-resistant efflux pumps than the N2 strain (22 vs 12). This also accounts for the broader resistance spectrum of N1 than of N2 in antimicrobial susceptibility tests. Additionally, both genomes contain numerous mobile genetic elements (89 and 21 genes, respectively) and virulence factors (276 and 250 factors, respectively), suggesting their potential for horizontal transfer and pathogenicity. Overall, this research provides insights into the potential risks posed by ARBs in pharmaceutical wastewater and emphasizes the need for further studies on their impact and mitigation strategies.

2024-10-20 | E-MTAB-14497 | biostudies-arrayexpress

Project description:Multidrug-Resistant Bacteria Isolated from Urban Wastewater Effluent

| PRJNA1246262 | ENA

Project description:Phages against multidrug-resistant bacteria

| PRJNA972335 | ENA

Characterization of (broad-host-range) bacteriophages targeting multidrug-resistant E. coli and Shigella spp.: in vitro Potential

Project description:bacteriophages targeting multidrug-resistant bacteria

| PRJEB83222 | ENA

Project description:Multidrug-resistant Gram-negative bacteria

| PRJNA438531 | ENA

Project description:Characterization of pathogenic multidrug resistant bacteria

| PRJNA847737 | ENA

Multidrug-resistant bacteria isolated from water

Project description:Multidrug-resistant bacteria isolated from water

| PRJEB29745 | ENA

2-DE based proteomics of spleen

Project description:The proteome of BALB/c mice infected with multidrug-resistant V. parahaemolyticus were investigated using spleens, which were stimulated by more bacteria than other organs

2023-06-12 | PXD042893 |

Antibiotic Resistance Profile and Genomic Characteristics of Multidrug-Resistant Bacteria from the Sludge of a Pharmaceutical Wastewater Treatment Plant

Project description:In this study, two multiantibiotic-resistant bacteria, Ochrobactrum intermedium (N1) and Stenotrophomonas acidaminiphila (N2), were isolated from the sludge of a PWWTP in Guangzhou, China. Whole-genome sequencing revealed that N1 and N2 had genome sizes of 0.52 Mb and 0.37 Mb, respectively, and harbored 33 and 24 ARGs, respectively. The main resistance mechanism in the identified ARGs included efflux pumps, enzymatic degradation, and target bypass, with the N1 strain possessing more multidrug-resistant efflux pumps than the N2 strain (22 vs 12). This also accounts for the broader resistance spectrum of N1 than of N2 in antimicrobial susceptibility tests. Additionally, both genomes contain numerous mobile genetic elements (89 and 21 genes, respectively) and virulence factors (276 and 250 factors, respectively), suggesting their potential for horizontal transfer and pathogenicity.

2024-10-20 | E-MTAB-14496 | biostudies-arrayexpress

Multidrug-resistant Shigella sonnei in Spain

Project description:Multidrug-resistant Shigella sonnei in Spain: an ever-evolving problem?

| PRJEB51813 | ENA