Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

IL-10 suppresses T cell expansion while promoting tissue-resident memory cell formation during SARS-CoV-2 infection in rhesus macaques

ABSTRACT: IL-10 suppresses T cell expansion while promoting tissue-resident memory cell formation during SARS-CoV-2 infection in rhesus macaques

PROVIDER: PRJNA1115095 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

IL15 in treatment of rhesus macaques

Project description:Rhesus macaques vaccinated by rhesus cytomegalovirus vectors expressing simian immunodeficiency virus proteins (RhCMV/SIV) activate gene expression signature associated with IL15. To examine the gene expression signature activated by IL15, we performed longitudinal examinations of rhesus macaques during IL15 treament.

2021-06-28 | GSE160577 | GEO

Dramatic effects of social behavior on gene regulation in rhesus macaques

Project description:This SuperSeries is composed of the following subset Series: GSE33090: Dramatic effects of social behavior on gene regulation in rhesus macaques [Individual_expression] GSE34127: Dramatic effects of social behavior on gene regulation in rhesus macaques [Cell type_expression] GSE34128: Dramatic effects of social behavior on gene regulation in rhesus macaques [Bisulfite_seq] Refer to individual Series

2012-02-01 | E-GEOD-34129 | biostudies-arrayexpress

BCG vaccination in rhesus macaques

Project description:BCG vaccination in rhesus macaques

| PRJNA902836 | ENA

Dramatic effects of social behavior on gene regulation in rhesus macaques [Cell type_expression]

Project description:Analysis of gene expression differences in relationship to dominance rank in female rhesus macaques. RNA obtained from 4 cell populations (helper T cells, cytotoxic T cells, monocytes, and B cells) from isolated peripheral blood mononuclear cells sampled from 5 adult female rhesus macaques across 5 different social groups and 5 different dominance ranks [dominance ranks : 1 = high, 5 = low]

2012-02-01 | E-GEOD-34127 | biostudies-arrayexpress

Dramatic effects of social behavior on gene regulation in rhesus macaques [Cell type_expression]

Project description:Analysis of gene expression differences in relationship to dominance rank in female rhesus macaques.

2012-02-01 | GSE34127 | GEO

Blood DNA methylation data of newborn rhesus macaques

Project description:Methylomic profiling of rhesus macaque blood samples. The Illumina Infinium MethylationEPIC kit was used to obtain DNA methylation profiles for over 850,000 CpGs, of which 339,081 were determined to be conserved in rhesus macaques based on the Mmul_10 genome build. A total of 29 samples were included, of which 26 remained after processing.

2025-04-15 | GSE201215 | GEO

Dramatic effects of social behavior on gene regulation in rhesus macaques [Individual_expression]

Project description:Analysis of gene expression differences in relationship to dominance rank in female rhesus macaques. RNA obtained from isolated peripheral blood mononuclear cells from 49 adult female rhesus macaques of dominance ranks 1 (high) to 5 (low) across 10 social groups. Total 100 samples = (47 individuals X 2 replicates) + (2 individuals X 3 replicates)

2012-02-01 | E-GEOD-33090 | biostudies-arrayexpress

Single cell study on PBMCs from Rhesus macaques treated with IL-15/IL-15Ra

Project description:This single cell RNA-seq experiment is designed to understand the IL-15 response in PBMCs from Rhesus macaques

2025-08-01 | GSE291887 | GEO

Blood transcriptome following intravenous BCG vaccination in rhesus macaques

Project description:To determine the blood transcriptional response to intravenous (IV) BCG vaccination in rhesus macaques and identify correlates of vaccine-mediated protection against Mycobacterium tuberculosis (Mtb) challenge.

2023-06-19 | GSE218270 | GEO

High-throughput Ig and TCR repertoire single-cell sequencing analysis in rhesus macaques

Project description:Recent advancements in microfluidics and high-throughput sequencing technologies have enabled recovery of paired heavy- and light- chain of immunoglobulins (Ig) and VDJ- and VJ- chains of T cell receptors (TCR) from thousands of single cells simultaneously. Due to the complexity of these polyclonal receptors, for many species single-cell immune repertoire sequencing assays are not yet commercially available. Rhesus macaques are one of the most well-studied model organisms of the human adaptive immune response; application of these new immune repertoire sequencing assays is highly relevant to vaccine and infectious disease studies. Here we use custom designed primers to target and enrich for every known Ig and TCR chain and isotype in the rhesus macaque animal model. We sequenced more than 110,000 cell barcodes from rhesus macaque repertoires using PBMC, splenocyte, and FACS-sorted T and B cell. We were able to recover every Ig and TCR isotype, measure clonal expansion in proliferating T cells, and pair repertoires with gene expression profiles of single cells. Our results establish the ability to perform single-cell based immune repertoire analysis in rhesus macaque.

2021-11-18 | GSE179722 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data