Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Temporal dynamics of gene expression during metamorphosis in two distant Drosophila species

ABSTRACT: Temporal dynamics of gene expression during metamorphosis in two distant Drosophila species

PROVIDER: PRJNA1124160 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR29422300_1.fastq.gz	Fastqsanger.gz
	SRR29422300_2.fastq.gz	Fastqsanger.gz
	SRR29422301_1.fastq.gz	Fastqsanger.gz
	SRR29422301_2.fastq.gz	Fastqsanger.gz
	SRR29422302_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 120

Similar Datasets

Temporal dynamics of gene expression during metamorphosis in two distant Drosophila species

Project description:Complete metamorphosis of holometabolous insects is a complex biological process characterized by profound morphological, physiological, and transcriptional changes. To reveal the temporal dynamics of gene expression during this critical developmental transition, a detailed analysis of the developmental transcriptomes of two Drosophila species, Drosophila melanogaster and Drosophila virilis, was conducted. We confirm partial recapitulation of the embryonic transcriptional program in pupae, but instead of the traditional hourglass model, which posits maximal conservation at mid-embryonic stages, at different stages of pupae we observe a more complicated pattern of alternating low and high diversity, resembling an inverted hourglass, or "spindle". This observation challenges the notion of a singular conserved phylotypic period during holometabola ontogeny and underscores the complexity of developmental processes during complete metamorphosis. Notably, recently formed genes (specific to insects) exhibit pronounced expression peaks during mid-pupal development, underscoring their potential role in developmental transitions.

2024-06-17 | GSE269951 | GEO

Proteomic analysis of ascidian metamorphosis

Project description:Shallow-water ascidians are prevalent invasive and fouling organisms within marine ecosystems. Their larvae undergo rapid metamorphosis from planktonic to sessile stage, facilitating colonization and population expansion. It is crucial to explore the molecular and cellular orchestration of larval metamorphosis in order to gain a deep understanding of ascidian environmental adaptability, as well as to develop effective methods for bioinvasion and biofouling control. Here, we conducted 4D-label free quantitative proteomics combined with transcriptomics to monitor protein and gene expression across five distinct developmental stages from swimming larva to metamorphic juvenile of ascidian Ciona. We identified a total of 6,043 proteins, approximately 83.6% of which were quantified. We delineated the temporal dynamics of protein expression during ascidian metamorphosis and identified differentially expressed proteins between stages.

2026-01-10 | PXD061044 | Pride

Temporal dynamics grapevine rootstocks

Project description:Temporal dynamics - grapevine rootstocks Raw sequence reads

| PRJNA776141 | ENA

The transcriptional dynamics of Ophryocystis elektroscirrha across its host's metamorphosis

Project description:The transcriptional dynamics of Ophryocystis elektroscirrha across its host's metamorphosis

| PRJNA1137938 | ENA

DNA methylation dynamics associated with visual system remodeling during flatfish metamorphosis

Project description:Flatfish metamorphosis is characterized by extensive tissue remodeling, associated with a transition from pelagic to benthic lifestyle, being the migration of one eye the most dramatic change. Epigenetic mechanisms exert a pivotal role in developmental programs. This study investigates the DNA methylation profiles of migrating and non-migrating eyes using reduced-representation bisulfite sequencing (RRBS) during three developmental stages of turbot: pre-metamorphosis, climax and post-metamorphosis. Over 31% of all identified regions were hypermethylated during climax stage in both eyes, coinciding with elevated expression of the dnmt3a gene, responsible for de novo methylation. Additionally, transcription factors crucial for retinal ganglion cells (RGCs) development, including the eomesa and tbr1b, exhibited differential methylation and expression between the migrating and non-migrating eye during the climax phase. These findings underscore the significance of DNA methylation in the intricate remodeling of the visual system during turbot metamorphosis, particularly regarding RGC-mediated ocular migration and the transmission of visual signals.

2025-12-04 | GSE291550 | GEO

The transcriptional dynamics of Ophryocystis elektroscirrha across its host's metamorphosis

Project description:The objective of this study was to quantify patterns of transcriptional differentiation that Ophryocystis elektroscirrha undergoes throughtout its host's metamorphosis.

2024-07-19 | GSE272670 | GEO

Temporal dynamics of intragenomic coevolution

Project description:Temporal dynamics of bacteria-plasmid coevolution under antibiotic selection

| PRJEB28173 | ENA

DNA methylation dynamics associated with visual system remodeling during flatfish metamorphosis

Project description:DNA methylation dynamics associated with visual system remodeling during flatfish metamorphosis

| PRJNA1234131 | ENA

Insect hormone prothoracicotropic hormone (PTTH) regulates lifespan through temporal and spatial activation of NF-κB signaling during Drosophila metamorphosis [1]

Project description:The prothoracicotropic hormone (PTTH) is a well-known neuropeptide that regulates insect metamorphosis (the juvenile-to-adult transition) by inducing the biosynthesis of steroid hormones, similar to the hypothalamic-pituitary-gonadal control of mammalian puberty. However, the role of Ptth in adult physiology and longevity is largely unexplored. Here, we show that Ptth loss-of-function mutants are long-lived and exhibit increased resistance to oxidative stress in Drosophila. Intriguingly, we find that loss of Ptth blunt age-dependent upregulation of NF-κB signaling specifically in fly oenocytes, the homolog of mammalian hepatocytes. We further show that oenocyte-specific overexpression of NF-κB/Relish blocks the lifespan extension of Ptth mutants, suggesting that Ptth regulates lifespan through oenocyte-specific NF-κB signaling. Surprisingly, adult-specific knockdown of Ptth did not prolong lifespan, indicating that Ptth might control longevity through developmental programs. Our developmental transcriptomic analysis reveals an interesting activation of NF-κB signaling during fly metamorphosis, which is attenuated in Ptth mutants. Intriguingly, the knockdown of NF-κB/Relish, specifically in oenocytes during metamorphosis, significantly prolongs the lifespan of adult flies. Thus, our findings uncover an unexpected role of insect hormone PTTH in controlling adult lifespan through temporal and spatial activation of NF-κB signaling in developing hepatocytes.

2025-04-22 | GSE271165 | GEO

Insect hormone prothoracicotropic hormone (PTTH) regulates lifespan through temporal and spatial activation of NF-κB signaling during Drosophila metamorphosis [2]

2025-04-22 | GSE271166 | GEO