Ontology highlight
ABSTRACT:
PROVIDER: PRJNA1137891 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:We collected whole genome testis expression data from hybrid zone mice. We integrated GWAS mapping of testis expression traits and low testis weight to gain insight into the genetic basis of hybrid male sterility. Gene expression was measured in whole testis from males aged 62-86 days. Samples include 190 first generation lab-bred male offspring of wild-caught mice from the Mus musculus musculus - M. m. domesticus hybrid zone.
2014-12-04 | E-GEOD-61417 | biostudies-arrayexpress
Project description:We collected whole genome testis expression data from hybrid zone mice. We integrated GWAS mapping of testis expression traits and low testis weight to gain insight into the genetic basis of hybrid male sterility.
2014-12-04 | GSE61417 | GEO
Project description:Ramphocelus hybrid zone
| PRJNA725153 | ENA
Project description:This study aimed to uncover changes in gene expression in key brain regions associated with social bonding neuroplasticity in adult prairie voles. The experimental workflow involved the following steps: 1. Male (Ma) and female (Fe) prairie voles were subjected to social cohabitation and mating (SCM) conditions for 120 h, with isolated animals serving as controls. 2. RNA was extracted and analyzing RNA from three brain regions crucial for social bonding and neuroplasticity: the subventricular zone (SVZ), dentate gyrus (DG), and nucleus accumbens (NAc). 3. RNA sequencing was performed to identify differentially expressed genes between the SCM and control groups. 4. Gene ontology (GO) and functional enrichment analyses were performed to understand the biological processes involved in pair bonding. 5. Validation of key findings through quantitative PCR and in vitro neurosphere assays using cells isolated from the SVZ. This approach allowed the examination of sex-specific changes in gene expression related to neurogenesis, synaptic plasticity, and other probable molecular pathways involved in pair bond formation, with potential implications for understanding human relationships and related neuropsychiatric conditions.
2025-05-15 | E-MTAB-15128 | biostudies-arrayexpress
Project description:Chloroplast genomes of the Populus trichocarpa x Populus balsamifera hybrid zone
| PRJNA1068052 | ENA
Project description:Total genomic DNAs of J118, CdUM4b, the pseudotetraploid hybrid strain HBT1 and the progeny hybrid strain HBP1 were isolated. In an attempt to determine the number of copies of individual chromosomes, we used comparative genome hybridization (CGH) analysis using specially designed whole genome microarrays representing C. albicans and C. dubliniensis genomes. The arrays contained 60 mer probes that fell in three categories either C. albicans specific or C. dubliniensis specific or common to both. The specific probes were expected to work as internal controls when hybridized to parental genomic DNA alone. The arrays were individually hybridized to Cy3-labeled genomic DNA from either of C. albicans (J118), C. dubliniensis (CdUM4b) parents or the somatic psudotetraploid hybrid strain, HBT1 and the pseudodiploid progeny hybrid HBP1. After experimentally determining species-specific probes and common probes, the ratios of intensity on the HBT1 hybrid array to those of either of the parents were calculated. The copy number was determined for the entire chromosomes by comparing individual probe intensities from the pseudotetraploid to either diploid parent genome DNA intensities.
2010-12-31 | GSE24269 | GEO