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ABSTRACT: RNA sequencing of mouse adipose tissue in response to dietary methionine restriction

PROVIDER: PRJNA1168893 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR30886000_1.fastq.gz	Fastqsanger.gz
	SRR30886000_2.fastq.gz	Fastqsanger.gz
	SRR30886001_1.fastq.gz	Fastqsanger.gz
	SRR30886001_2.fastq.gz	Fastqsanger.gz
	SRR30886002_1.fastq.gz	Fastqsanger.gz

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Project description:Dietary methionine restriction (MR) has been shown to increase lifespan and decrease adiposity in rodents. This study was designed to examine the transcriptional effects of MR in metabolically relevant tissues. This experiment contains data from the inguinal white adipose tissue (IWAT). We analyzed MR-induced changes in gene expression using pooled RNA from IWAT of rats fed either a control purified amino acid diet (DL-methionine content of 0.86%) (CON) or a methionine-restricted diet (DL-methionine content of 0.172%)(MR). Rats were fed Purina rodent diet 5001 until 32 days of age and were then randomly assigned to be fed CON diet or MR diet for 20 months.

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