Project description:This study is to compare the mRNA expression differences between atherosclerosis and non-atherosclerosis samples from female peripheral blood. The possible effects of races are also considered.
Project description:Genome-wide DNA methylation screening was performed using the Infinium HumanMethylation450 BeadChip in 34 samples of non-cancerous pancreatic tissue and 82 samples of cancerous tissue samples obtained from 82 patients with pancreatic ductal adenocarcinoma.
Project description:Atherosclerosis is fundamental in the development of cardiovascular disease. The unhealthy dietary habits, high fat and cholesterol intake could change the composition of gut microbes and metabolites which play a critical role in the development of atherosclerosis. To characterize the functionality of intestinal microbiome in the AS, we performed an analysis of microbiota proteins by a metaproteomics technique in 6 control samples and 6 feces samples. Using data dependent acquisition (DDA), a total of 8467 peptides with taxonomy annotation were identified and which were correspond to 3851 protein groups.
Project description:Eighteen samples were obtained from 9 patients who underwent delayed resection. The purpose of this study is to identify transcriptomic shifts in samples during therapy.
Project description:The microarray gene expression profiles of human carotids with advanced atherosclerosis obtained at autopsy (n=4) were compared with those obained at vascular surgery (n=3).