Project description:We have discovered a novel splicing regulatory factor. When this gene is knocked out in Drosophila, the flies exhibit drooping wings, disrupted muscle structure, and numerous aberrant splicing events in the neuromuscular system. Based on the wing phenotype observed in Drosophila, we have named this gene anw (angle wing).Our research focuses on investigating the mechanism of how Anw regulates alternative splicing.
Project description:Profiled chromatin accessibility and gene expression in the wing imaginal discs of Drosophila melanogaster, in wild type and nub[1] animals. We demonstrate using RNA-seq that expression of both nub and pdm2 paralogs are reduced in the nub[1] condition, and that this allele contains a previously unannotated deletion within the intergenic region between of nub and pdm2 using ATAC-seq that corresponds to a wing enhancer element.
Project description:Study of genome-wide differential gene expression of Drosophila Melanogaster Myb mutant wing discs of 3rd instar larvae compared to control animals.
Project description:To identify the cuticular proteins in developing wing scales of Bombyx mori, we performed LC-MS/MS analysis of dissoliving developing wing scales from Bombyx mori
Project description:Study of genome-wide differential gene expression of Drosophila Melanogaster Myb mutant wing discs of 3rd instar larvae compared to control animals.
Project description:Study of genomic distribution of RNA polymerase in Drosophila melanogaster Myb mutant wing discs of 3rd instar larvae compared to control animals.
2020-03-12 | GSE100138 | GEO
Project description:whole-genome resequencing of angel wing duck
Project description:We performed a genome-wide ChIP analysis to find the set of target genes regulated by Cbt in Drosophila wing imaginal discs. We reported multiple transcriptional regulators and genes involved in the developlment, growth and patterning of the fruit fly.
Project description:Wing imaginal discs were dissected to generate body wall and wing/hinge fragments. Targets from three biological replicates of each were generated and the expression profiles were determined using Affymetrix Drosophila Genechip 1 arrays. Comparisons between the sample groups allow the identification of genes with localized expression patterns. Keywords = Drosophila, wing disc, spatially restricted transcripts Keywords: repeat sample