Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

H2A.Z distribution and chromatin accessibility within human aortic smooth muscle cell [HASMC_ScienCell_CutTag]

ABSTRACT: H2A.Z distribution and chromatin accessibility within human aortic smooth muscle cell [HASMC_ScienCell_CutTag]

PROVIDER: PRJNA1214248 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

H2A.Z distribution and chromatin accessibility within human aortic smooth muscle cell [HASMC_ScienCell_CutTag]

Project description:We report the genome wide distribution of H2A.Z and chromatin accessibilty profile within human aortic smooth cells

2025-05-29 | GSE287687 | GEO

Transcriptome accessment of human aortic smooth muscle cell and rat aortic smooth muscle cell [HASMC_RASMC_RNASeq]

Project description:We report the transcriptome within human aortic smooth muscle cell and rat aortic smooth muscle cell. Some of the cells were treated with cholesterol.

2025-05-29 | GSE287684 | GEO

H2a.z, pol II and histone modification status within RASMC [RASMC_CutTag]

Project description:We report genome wide distribution of H3K27me3, H2a.z and pol II within RASMC. We also report genome wide distribution of H3K27ac, H3K4me3, pol II within RASMC after H2a.z knockdown down

2025-05-29 | GSE287685 | GEO

Chromatin accessibility in human aortic smooth muscle cells

Project description:We report the chromatin accessibilty profile within human aortic smooth cells

2025-05-29 | GSE286053 | GEO

Smooth muscle cell reprogramming in aortic aneurysms [RNA-Seq]

Project description:Smooth muscle cell TGFβ signaling is one of the primary drivers of smooth muscle cell maturation. Inhibition of smooth muscle cell TGFβ signaling in hyperlipidemic mice induces vessel wall inflammation and vessel wall dilation/dissection and leads aortic aneurysm. We performed bulk RNAseq method to examine smooth muscle cell gene expression profile using fresh human tissues from normal aortic media smooth muscle cells and aneurysm aortic media smooth muscle cells.

2020-03-01 | GSE140947 | GEO

Transcriptome accessment of human aortic smooth muscle cell and rat aortic smooth muscle cell [HASMC_RASMC_RNASeq]

Project description:Transcriptome accessment of human aortic smooth muscle cell and rat aortic smooth muscle cell [HASMC_RASMC_RNASeq]

| PRJNA1214245 | ENA

Transcription profiling of human aortic smooth muscle cells exposed to hypoxia

Project description:Systemic arterial smooth muscle cells are exposed to a broad range of oxygen concentrations under physiological conditions. Hypoxia can modulate the proliferative response of smooth muscle cells leading to speculation about its role in vasculogenesis, vascular remodelling and the pathogenesis of arterial disease. The effect of hypoxia has been inconsistent, however, with both enhanced proliferation and growth arrest reported. Nevertheless, these reports support an important effect of hypoxia on smooth muscle cell proliferation and, given its physiological and clinical relevance, this requires clarification. We posited that variation in O2 concentration, within the range that exists in vivo, may have different effects on the proliferation and survival of vascular smooth muscle cells. Experiment Overall Design: Human aortic smooth muscle cells (HASMC) were propagated to passage 6 in SMGM-2 medium reached 80% confluence, the media was changed and the cells were incubated for a further 16 hrs or 48 hrs under either normoxic or hypoxic conditions (1% and 3%O2 ).

2008-06-13 | E-GEOD-4725 | biostudies-arrayexpress

Smooth muscle cell-specific Klf4 deletion in Marfan syndrome aortic root aneurysm

Project description:Aortic smooth muscle cell (SMC) phenotype modulation is a central feature of cell-mediated pathology in Marfan syndrome aortic aneurysm and Klf4 is proposed to contribute to this process. We generated mice with smooth muscle cell-specific Klf4 deletion using an Myh11-creERT2 transgene, induced deletion at 8 weeks and performed single cell RNA sequencing at 24 weeks on whole aortic root tissues.

2022-08-23 | GSE206227 | GEO

Smooth muscle cell reprogramming in aortic aneurysms [scRNA-Seq]

Project description:Smooth muscle cell TGFβ signaling is one of the primary drivers of smooth muscle cell maturation. Inhibition of smooth muscle cell TGFβ signaling in hyperlipidemic mice induces vessel wall inflammation and vessel wall dilation/dissection and leads aortic aneurysm. We performed scRNAseq method to examine smooth muscle cell gene expression profile using Apoe and SMC specific TGFbR2 KO in Apoe background mice.

2020-03-01 | GSE141031 | GEO

Smooth muscle cell reprogramming in aortic aneurysms

Project description:Smooth muscle cell reprogramming in aortic aneurysms

| PRJNA591801 | ENA