Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

6K-plex RNA CosMx data from DLBCL sections.

ABSTRACT: 6K-plex RNA CosMx data from DLBCL sections.

PROVIDER: PRJNA1221889 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

6K-plex RNA CosMx data from DLBCL sections.

Project description:Diffuse large B-cell lymphomas (DLBCLs) are a common and heterogeneous group of mature B-cell malignancies that typically arise in lymph nodes; sites in which stromal and endothelial cells, antigen-presenting cells and other myeloid cells facilitate adaptive immune responses by T-cells and B-cells against pathogens. In this study, we have leveraged the spatial transcriptomic platform of CosMx together with CODEX imaging technology to investigate the spatial immunology and pathobiology of DLBCL.

2025-05-26 | GSE289194 | GEO

Nanostring CosMx 6,000-plex RNA profiling of human kidney nephrectomy specimens

Project description:Nanostring CosMx 6,000-plex RNA profiling of human kidney nephrectomy specimens

| PRJNA1186729 | ENA

Nanostring CosMx 980-plex RNA profiling of human kidney biopsy and nephrectomy

Project description:Nanostring CosMx 980-plex RNA profiling of human kidney biopsy and nephrectomy

| PRJNA1065804 | ENA

Nanostring CosMx 6,000-plex RNA profiling of human kidney nephrectomy specimens

Project description:The human kidneys are comprised of multiple different cell types in a complex anatomical arragemnt that is optimal for their key functions such as waste removal, regulation of fluid and electrolyte homeostasis and production of hormones. In chronic kidney disease (CKD) this arrangement is disrupted with de-differentiation and atrophy of epithelial cells, recruitment of immune cells and activation of myofibroblasts to produce excess scarring. A better understanding of cellular phenotypes, complex intercellular communication and intracellular signaling pathways that promote CKD could lead to development of novel therapies. We applied single-cell spatial transcriptomics (CosMx Spatial molecular imaging) to human kidney neprectomy speciemens with unilateral ureteral obstruction (UUO, n=5) and healthy kidneys (n=2).

2025-03-20 | GSE282059 | GEO

Drug combination sci-Plex Data

Project description:Drug combination sci-Plex Data

| PRJNA851906 | ENA

Nanostring CosMx 980-plex RNA profiling of human kidney biopsy and nephrectomy

Project description:The human kidneys are comprised of multiple different cell types in a complex anatomical arragemnt that is optimal for their key functions such as waste removal, regulation of fluid and electrolyte homeostasis and production of hormones. In chronic kidney disease (CKD) this arrangement is disrupted with de-differentiation and atrophy of epithelial cells, recruitment of immune cells and activation of myofibroblasts to produce excess scarring. A better understanding of cellular phenotypes, complex intercellular communication and intracellular signaling pathways that promote CKD could lead to development of novel therapies. We applied single-cell spatial transcriptomics (CosMx Spatial molecular imaging) to human kidney biopy and nephrectomy samples from patients with IgA nephropathy (n=6), minimal change disease (n=3) and advanced pyelonephritis (n=4).

2025-03-25 | GSE253439 | GEO

IBD CosMx NanoString data from colonic mucosa

Project description:Inflammatory bowel diseases (IBDs) including ulcerative colitis (UC) and Crohn’s disease (CD) are chronic inflammatory diseases with increasing worldwide prevalence that show a perplexing heterogeneity in manifestations and response to treatment. We applied spatial transcriptomics at single-cell resolution (CosMx Spatial Molecular Imaging) to human inflamed and uninflamed intestine.

2023-06-13 | GSE234713 | GEO

IBD CosMx NanoString data from colonic mucosa

Project description:IBD CosMx NanoString data from colonic mucosa

| PRJNA982807 | ENA

DLBCL

Project description:DLBCL

| PRJNA1118307 | ENA

Cosmx Spatial Analysis of whole brain slices and ventral pallidum

Project description:Pilot Cosmx experiment to explore and spatially atlas cell types present in the Striatum

2025-03-31 | GSE292791 | GEO