Lactiplantibacillus plantarum
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA1225732 | ENA |
REPOSITORIES: ENA
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| Other | ||||
| SRR32726422_1.fastq.gz | Fastqsanger.gz | |||
| SRR32726422_2.fastq.gz | Fastqsanger.gz | |||
| SRR32726423_1.fastq.gz | Fastqsanger.gz | |||
| SRR32726423_2.fastq.gz | Fastqsanger.gz |
Items per page: 5 1 - 5 of 9 |
Similar Datasets
Project description:The transcriptome of L. plantarum strains that aggregate was compared with non-aggregating strains
2021-04-20 | GSE172351 | GEO
Project description:Probiotics have been suggested to ameliorate the function of the intestinal epithelial barrier and so have several mediators and receptors of the expanded endocannabinoid system, the endocannabinoidome (eCBome). Here we cocultured three live strains of Lactiplantibacillus plantarum with intestinal epithelial organoids to study their effects on the gut barrier function and the possible involvement of the eCBome in this effect. All three L.plantarum strains variously reduced the trans-epithelial permeability of intestinal organoids and promoted increased mRNA expression of several tight junction proteins and intestinal barrier proteins. Concomitantly, the three strains upregulated the expression of genes encoding biosynthetic enzymes (i.e., NapePLD, Abdh4, Gde1, Daglb) and receptors (i.e., Cnr1, Cnr2, Gpr55, and Ppara), while concurrently downregulating the expression of two essential catabolic enzymes (i.e. Faah and Naaa), involved in the signaling of several eCBome mediators known for their role in regulating the intestinal epithelial barrier. Selective inhibitors of eCBome mediator degrading enzymes FAAH and MAGL, i.e., URB597 and JZL184, increased N-acyl-ethanolamine (NAE) and 2-monoacylglycerol (2-MAG) levels, respectively, enhanced the expression of intestinal epithelial barrier genes and reduced the trans-epithelial permeability of organoids, as for L. plantarum strains. Interestingly, inflammation-induced trans-epithelial permeability in organoids was also reversed by both FAAH and MAGL inhibitors. We surmise that elevated endogenous levels of either NAEs or 2-MAGs promote improvement in small intestine trans-epithelial permeability and that L. plantarum strains may exploit this mechanism to promote these beneficial effects.
2025-01-31 | GSE263720 | GEO
Project description:The WYL transcription factor (LP_RS00300) is a c-di-GMP effector in L. plantarum WCFS1. LP_RS00300 binds to a special motif within the coding sequence, impeding the transcriptional elongation of LP_RS05345 and LP_RS05225, which encode mucus binding proteins (MucBPs). The perception of c-di-GMP by the WYL domain reversed the inhibitory effect of LP_RS00300 on the expression of MucBPs, resulting in increased adherence to intestinal epithelial cells by L. plantarum. Overall, our study provides evidence that a WYL transcription factor participates in probiotic colonization by sensing c-di-GMP.
2025-02-14 | PXD053948 | Pride
Project description:WGS of Lactobacilli isolated from Iranian Motal cheese
| PRJNA692080 | ENA
Project description:The study was conducted on a model of Lactiplantibacillus plantarum, one of the most studied species widely used in the food industry as a probiotic microorganism and/or microbial starter culture. As a result of step-by-step selection from the L. plantarum 8p-a3 strain isolated from the «Lactobacterin» probiotic, the L. plantarum 8p-a3-Clr-Amx strain was obtained, showing increased resistance, compared with the parent strain, to amoxicillin-clavulanic acid (MIC 20 mcg/ml) and clarithromycin (MIC 10 mcg/ml). The L. plantarum strain DMC-S1 was isolated from the intestine of Drosophila melanogaster Canton-S line. Extracellular vesicles of this bacterium can play a significant role in the drug-resistance development and host-microbe interactions.
2023-11-01 | PXD046569 | JPOST Repository
Project description:This project uses TMT labeling quantitative proteomics technology to carry out research, and a total of 898 proteins have been identified. Differentially expressed proteins were screened according to the criteria of expression fold change of more than 1.5-fold (up-regulation more than 1.5-fold or down-regulation less than 0.67) and P value<0.05. Among them, taking the comparison group Control VS H2O2 as an example, there were 31 up-regulated differentially expressed proteins and 81 down-regulated differentially expressed proteins. Through GO enrichment and KEGG pathway analysis, it was found that these differentially expressed proteins are mainly involved in important biological processes such as single-organism metabolic process, small molecule metabolic process, organophosphate metabolic process, organophosphate biosynthetic process and carbohydrate derivative biosynthetic process, and are mainly involved in the regulation of Metabolic pathways, Fructose and mannose metabolism, Oxidative phosphorylation, Tyrosine and Degradation of aromatic compounds and other important KEGG metabolic pathways.
2022-08-12 | PXD032910 | Pride
Project description:Trascriptomic profiles of Lactobacillus plantarum strains isolated from cheeses
| PRJNA393838 | ENA
Project description:Lactobacillus plantarum strains isolated from porcine feces, genome sequencing and assembly
| PRJNA287726 | ENA
Project description:Lactiplantibacillus plantarum has a strong carbohydrate utilization ability. This characteristic plays an important role in its gastrointestinal tract colonization and probiotic effects. L. plantarum LP-F1 presents a high carbohydrate utilization capacity. The genome analysis of 165 L. plantarum strains indicated the species has a plenty of carbohydrate metabolism genes, presenting a strain specificity. Furthermore, two-component systems (TCSs) analysis revealed that the species has more TCSs than other lactic acid bacteria, and the distribution of TCS also shows the strain specificity. In order to clarify the sugar metabolism mechanism under different carbohydrate fermentation conditions, the expressions of 27 carbohydrate metabolism genes, catabolite control protein A (CcpA) gene ccpA, and TCSs genes were analyzed by quantitative real-time PCR technology. The correlation analysis between the expressions of regulatory genes and sugar metabolism genes showed that some regulatory genes were correlated with most of the sugar metabolism genes, suggesting that some TCSs might be involved in the regulation of sugar metabolism.
| S-EPMC8704671 | biostudies-literature
Project description:The aim of this work was to gain insight into the mechanisms involved in the immunomodulatory properties of L. rhamnosus CRL1505 and L. plantarum CRL1506 in the context of TLR4-mediated inflammation, particularly focused on macrophages. Therefore, in vitro studies in murine macrophages were conducted to evaluate the ability of the lactobacilli strains to modulate the transcriptomic response after LPS stimulation.
2025-03-25 | GSE288790 | GEO