Project description:Rats were given pulmonary embolism by i.v. injection of 25 micron polystyrene microspheres or 0.01% Tween20 solution as vehicle control Embolism of microspheres is irreversible and causes dose dependent pulmonary hypertension Keywords: time course and dose response

2009-09-01 | GSE13535 | GEO

Blood transcriptional profiling in a prospective observational cohort of South African adults referred for investigation of possible pulmonary tuberculosis

Project description:Blood transcriptional profiling in a prospective observational cohort of South African adults referred for investigation of possible pulmonary tuberculosis

| PRJEB34211 | ENA

Large-scale non-targeted serum metabolomics in the Prospective Investigation of the Vasculature in Uppsala Seniors

Project description:The Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) is a community-based study where all men and women at age 70 living in Uppsala, Sweden were invited to participate in 2001. The 1,016 participants (50% women) have been extensively phenotyped. In March 2006 a reinvesigation of the cohort at the age of 75 was started. The major measurements performed at age 70 were also repeated at age 75. Here we make publically available all the metabolomics analysis on serum samples from the investigation at age 70. In the final analysis we included samples from 968 individuals.

2014-08-30 | MTBLS90 | MetaboLights

Transcription profiling of rat right heart pulmonary embolism vs control

Project description:Time and dose related expression profiles of rat right heart tissue in microsphere bead model for Pulmonary embolism Experiment Overall Design: Rat right tissues of the Vehicle(no beads- control), low dose and high dose from rat bead model for Pulmonary Embolism were collected after 2, 6 and 18 hour time points. The extracted RNA was hybridized to Affymetrix Rat 230-2.0 microarrays to look for the dose and/or time related transcriptional changes associated with experimental Pulmonary Embolism.

2008-10-18 | E-GEOD-6104 | biostudies-arrayexpress

Blood transcriptional profiling in a prospective observational cohort of South African adults presenting for investigation of possible pulmonary tuberculosis

Project description:Blood transcriptional signatures may discriminate individuals with tuberculosis (TB) from disease-free controls, or from patients with other infectious or respiratory diseases. To systematically evaluate the diagnostic accuracy of published transcriptional signatures in a clinically relevant population with high burden of TB and human immunodeficiency virus (HIV), adults presenting for investigation of possible pulmonary TB were consecutively recruited at a TB clinic in South Africa. At enrolment, peripheral blood was collected in Tempus tubes (for RNA sequencing) and patients provided two sputum samples (for Xpert and liquid culture). Amongst 181 patients (median age 35 years), 44 (24%) were infected with human immunodeficiency virus (HIV). 54 patients (30%) were diagnosed with Xpert- or culture-positive TB. No alternate diagnoses were available for Xpert- and culture-negative non-TB patients.

2020-03-17 | E-MTAB-8290 | biostudies-arrayexpress

A Prospective Natural History Study of Diagnosis, Treatment and Outcomes of Children with SCID Disorders - PIDTC 6901

Project description:A Prospective Natural History Study of Diagnosis, Treatment and Outcomes of Children with SCID Disorders - PIDTC 6901

| PRJNA392089 | ENA

Rat right heart pulmonary embolism microarray

Project description:Time and dose related expression profiles of rat right heart tissue in microsphere bead model for Pulmonary embolism Keywords: Time course and dose response in experimental PE

2008-07-01 | GSE6104 | GEO

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