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Raw datas of the transcriptome in livers of Hezuo pigs and Bama pigs

ABSTRACT: Raw datas of the transcriptome in livers of Hezuo pigs and Bama pigs

PROVIDER: PRJNA1258234 | ENA |

REPOSITORIES: ENA

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			Action	DRS
		Other
	SRR33413117_1.fastq.gz	Fastqsanger.gz
	SRR33413117_2.fastq.gz	Fastqsanger.gz
	SRR33413118_1.fastq.gz	Fastqsanger.gz
	SRR33413118_2.fastq.gz	Fastqsanger.gz

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Raw datas of the transcriptome in livers of Hezuo pigs and Bama pigs

Project description:This study selected cooperative pigs and Baoma pigs as the experimental subjects. By integrating the whole-transcriptome sequencing technology, the ceRNA network related to cold stress-induced anti-injury in the livers of cooperative pigs was screened. The aim was to reveal the molecular mechanism of maintaining liver functional homeostasis in cooperative pigs under cold stress conditions, and to provide new theoretical basis and technical support for cold resistance breeding and liver injury protection of livestock.

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Raw datas of the transcriptome in testes of Hezuo pigs and Landrace pigs at two different ages

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Raw datas of the transcriptome in testes of Hezuo pigs and Landrace pigs at two different ages

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Raw data of testicular small RNA-Seq in Hezuo pigs and Landrace pigs at two different ages

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2015-05-05 | E-GEOD-68489 | biostudies-arrayexpress

Comparative anterior pituitary miRNA and mRNA expression profiles of Bama minipigs and Landrace pigs reveal potential molecular network involved in animal postnatal growth [mRNA-Seq]

Project description:The anterior pituitary is the most important endocrine organ modulating animal postnatal growth, mainly by controlling growth hormone (GH) gene transcription, synthesis, and secretion. As an ideal model for animal postnatal growth studies, the Bama minipig is characterized as having a lower growth performance and fewer individual differences compared with larger pig breeds. In this study, anterior pituitaries from Bama minipig and Landrace pig were used for miRNA and mRNA expression profile analysis using miRNA microarrays and mRNA-seq. Consequently, a total of 222 miRNAs and 12,909 transcripts were detected, and both miRNAs and mRNAs in the two breeds showed high correlation (r > 0.97). Additionally, 41 differentially expressed miRNAs and 2,254 transcripts were identified. Pathways analysis indicated that 32 pathways significantly differed in the two breeds. Importantly, two GH-regulation-signalling pathways, cAMP and inositol 1, 4, 5-triphosphate (IP3), and multiple GH-secretion-related transcripts were significantly down-regulated in Bama minipigs. Moreover, target prediction by two algorithms (TargetScan and RNAhybrid) indicated that most miRNA–mRNA target pairs (63.68–71.33%) presented a negatively correlated expression pattern. A possible network among miRNAs, mRNAs, and GH-regulation pathways was also proposed. These data will be helpful in understanding the possible molecular mechanisms involved in animal postnatal growth. mRNA profiling in the anterior pituitary from two different pig breeds.2 pooled samples were analyzed. A pool of 3 pig anterior pituitary was used for Bama minpigs(YB) and Landrace pigs(YC),respectively.

2015-05-05 | E-GEOD-68490 | biostudies-arrayexpress

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