Pterocarpus marsupium
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA1299661 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:Pterocarpus marsupium Genome sequencing
| PRJNA1006531 | ENA
Project description:Transcriptome of Pterocarpus santalinus
| PRJNA782228 | ENA
Project description:As the molecular mechanisms of biological aging become better understood, there is growing interest in identifying interventions that target those mechanisms to promote extended health and longevity. The budding yeast Saccharomyces cerevisiae has served as a premier model organism for identifying genetic and molecular factors that modulate cellular aging and is a powerful system in which to evaluate candidate longevity interventions. Here we screened a collection of natural products and natural product mixtures for effects on the growth rate, mTOR-mediated growth inhibition, and replicative lifespan. No mTOR inhibitory activity was detected, but several of the treatments affected growth rate and lifespan. The strongest lifespan shortening effects were observed for green tea extract and berberine. The most robust lifespan extension was detected from an extract of Pterocarpus marsupium and another mixture containing Pterocarpus marsupium extract. These findings illustrate the utility of the yeast system for longevity intervention discovery and identify Pterocarpus marsupium extract as a potentially fruitful longevity intervention for testing in higher eukaryotes.
| S-EPMC8599564 | biostudies-literature
Project description:The first complete chloroplast genome (cpDNA) sequence of Pterocarpus macrocarpus was determined from Illumina HiSeq pair-end sequencing data in this study. The cpDNA is 154,734 bp in length, contains a large single copy region (LSC) of 88,418 bp and a small single copy region (SSC) of 18,790 bp, which were separated by a pair of inverted repeats (IR) regions of 23,763 bp. The genome contains 127 genes, including 84 protein-coding genes, 8 ribosomal RNA genes, and 35 transfer RNA genes. The overall GC content of the whole genome is 36.3%, and the corresponding values of the LSC, SSC, and IR regions are 33.8%, 30.2%, and 43.3%, respectively. Further phylogenomic analysis showed that P. macrocarpus in Pterocarpus genus clade in Papilionoideae subfamily.
| S-EPMC7748621 | biostudies-literature