Project description:To investigate the effect of METRNL on macrophages phagocytosis and killing of Candida albicans, we designed RNA-Seq analysis of macrophages pretreated with vehicle or rmMETRNL challenged with Candida albicans for 6 hours in vitro.
Project description:To investigate the effect of Progranulin on neutrophils phagocytosis and killing of Candida albicans, we designed RNA-Seq analysis of wild-type and PGRN-/- neutrophils challenged with Candida albicans in vitro at one time point.
Project description:To investigate the effect of progranulin on macrophages phagocytosis and killing of Candida albicans, we designed RNA-Seq analysis of wild-type and PGRN-/- macrophages challenged with Candida albicans in vitro at one time point.
Project description:To investigate the gene expression profilie of systemic Candida albicans infection(invasive candidiasis), we designed RNA-Seq analysis of peripheral blood mononuclear cells for Control mice(uinfected) and systemic Candida albicans-infected mice(infected for 7days).