Project description:Small RNAs are emerging as important molecules for cross-species communication. Thanks to available and affordable sequencing technologies it is now possible to sequence small RNAs (sRNA-Seq) present in samples of interacting organisms. A first step when analyzing sRNA-Seq of two interacting species is to determine which sequences are being produced by which organism. Due to their small size (18-30), small RNAs could easily map to both host and parasite genomes. Here we produced data for Mus musculus intestinal epithelial cells treated with Extracellular Vesicles (EV) produced by the parasitic nematode Heligmosomoides bakeri.
Project description:Transcription of oncogenes is regulated by co-factors, some of which are now targetable with small molecules. This series contains ChIP-Seq targeting transcriptional co-factors and RNA polymerase from cells treated with small molecules targeting co-factors.
Project description:Transcription of oncogenes is regulated by co-factors, some of which are now targetable with small molecules. This series contains ChIP-Seq targeting transcriptional co-factors and RNA polymerase from cells treated with small molecules targeting co-factors. ChIP-Seq of RNA polymerase and co-factors in Jurkat T-ALL cells
Project description:Global transcriptome profiling of triple-negative breast cancer cell lines treated with small-molecules targeting Bromodomain and Extra Terminal (BET) proteins