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Mus musculus

ABSTRACT: Expression data from Paneth cells isolated from mice on calorie restricted or ad libitum diet

OTHER RELATED OMICS DATASETS IN: E-GEOD-37209

PROVIDER: PRJNA158971 | ENA |

REPOSITORIES: ENA

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E-GEOD-37209

Project description:Expression data from Paneth cells isolated from mice on calorie restricted or ad libitum diet

2015-09-28 | E-GEOD-37209 | ExpressionAtlas

Expression data from Paneth cells isolated from mice on calorie restricted or ad libitum diet

Project description:Paneth cells recide in the intestinal crypt bottom and are part of the innate immunity and of the intestinal stem cell niche. We used microarrays to detail the global changes in gene expression following reduced calorie intake. Mice were kept on ad libitum or calorie restricted (60% of calories of ad libitum) diets for 4-7 weeks and paneth cells were isolated using flowcytometry

2012-04-11 | E-GEOD-37209 | biostudies-arrayexpress

E-GEOD-4786

Project description:Transcription profiling by array of cochleae from mice fed a calorie-restricted diet

2014-08-15 | E-GEOD-4786 | ExpressionAtlas

Mus musculus

Project description:Expression data from livers of ad libitum and calorie-restricted mice

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Transcriptome analysis in calorie-restricted rats implicates epigenetic and post-translational mechanisms in neuroprotection and aging

Project description:Using RNA-seq, 39 cerebral cortex RNA samples were sequenced. The study design was as follows: Ad libitum fed rats at 6 months (n=3, 6 individuals pooled), 12 months (n=3, 6 individuals pooled) and 28 months (n=3, 6 individuals pooled). Calorie restricted rats at 6 months (n=3, 6 individuals pooled), 12 months (n=3, 6 individuals pooled) and 28 months (n=3, 6 individuals pooled). Rats fed alpha lipoic acid as a supplement to ad libitum at 12 months (n=3, 6 individuals pooled) and 28 months (n=3, 6 individuals pooled). Diet switching groups, where diet was changes at 12 months; 28 month ad libitum switched to calorie restriction (n=3, 6 individuals pooled), 28 month calorie restriction switched to ad libitum (n=3, 6 individuals pooled), 28 month ad libitum plus lipoic acid switched to calorie restriction (n=3, 6 individuals pooled), 28 month calorie restriction switched to ad libitum plus lipoic acid (n=3, 6 individuals pooled).

2015-11-22 | GSE57110 | GEO

Remodeling of the protein ubiquitylation landscape in the aging vertebrate brain

Project description:Ubiquitylome data from brains of old mice either fed ad libitum or calorie restricted (4 weeks) followed by a refeeding phase (7days)

2024-10-28 | MSV000096229 | MassIVE

Remodeling of the protein ubiquitylation landscape in the aging vertebrate brain

Project description:Whole proteome data from brains of old mice either fed ad libitum or calorie restricted (4 weeks) followed by a refeeding phase (7days)

2024-10-28 | MSV000096226 | MassIVE

Transcriptome analysis in calorie-restricted rats implicates epigenetic and post-translational mechanisms in neuroprotection and aging

2015-11-22 | E-GEOD-57110 | biostudies-arrayexpress

Mouse adipose tissue under hypercaloric and isocaloric high-fat diet

Project description:The objective of the experiment was to dissect the effects of a high-fat diet on juvenile adipose tissue gene expression under conditions of excess calorie intake versus normal calorie intake in comparison to a standard low-fat diet. For this purpose juvenile mice were fed (A) a standard low-fat diet (CD), (B) a high-fat diet ad libitum (excess calorie intake) (HFD) and (C) a high-fat diet with calorie consumption restricted to the calorie consumption of the CD diet (R-HFD). RNA expression was profiled after 1 week of feeding in the periuterine fat depot.

2019-04-09 | E-MTAB-7755 | biostudies-arrayexpress

Effect of in utero undernutrition on skeletal muscle gene expression

Project description:In utero undernutrition is associated with obesity and insulin resistance, although its effect on skeletal muscle remains poorly defined. We report that, in mice, adult offspring from undernourished dams have decreased energy expenditure, decreased skeletal muscle mitochondrial content, and altered energetics in isolated mitochondria and permeabilized muscle fibers. Strikingly, when these mice are put on a 40% calorie restricted diet they lose half as much weight as calorie restricted controls. Our results reveal for the first time that in utero undernutrition alters metabolic physiology having a profound effect on skeletal muscle energetics and response to calorie restriction in adulthood. We have used a mouse model of low birth weight generated through 50% food restriction of mouse dams during the third week of gestation. We have studied in utero food restricted offspring and control offspring that were not food restricted in utero in both the ad libitum and calorie restricted states. Gene expression profiling was performed on tibialis anterior muscle from 8 mice per group, pooled in pairs.

2014-08-01 | E-GEOD-53520 | biostudies-arrayexpress

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