Mus musculus
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA172197 | ENA |
REPOSITORIES: ENA
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| SRR534623.fastq.gz | Fastqsanger.gz | |||
| SRR534624.fastq.gz | Fastqsanger.gz | |||
| SRR534625.fastq.gz | Fastqsanger.gz | |||
| SRR534626.fastq.gz | Fastqsanger.gz | |||
| SRR534627.fastq.gz | Fastqsanger.gz |
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Project description:Daily (circadian) clocks are essential for regulating and coordinating physiology in mammals. Modulation of local chromatin structure has been shown for only a small number of genes, principally thought to be directly modulated by Clock-mediated histone acetylation. Here we show that genome-wide changes of active and suppressive histone marks control global chromatin architecture over the day and night. Examination of mouse liver tissue at 4 time-points around the clock in "free-running", continuous conditions (constant darkness, temperature and food available ad libitum).
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