Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mus musculus

ABSTRACT: Expression data from WT, E2f8 KO, Rb KO and Rb E2f8 DKO spleen Ter19+CD71high sorted cells

OTHER RELATED OMICS DATASETS IN: E-GEOD-52157

PROVIDER: PRJNA227047 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Expression data from WT, E2f8 KO, Rb KO and Rb;E2f8 DKO spleen Ter19+CD71high sorted cells

Project description:To understand molecular mechanisms underlying the synergy of Rb loss and E2F8 loss, we used gene expression profiling to assess molecular changes in Mx1-Cre-mediated knockout (KO) mice using RNA isolated from sorted Ter119+CD71high Erythroblasts. The top four upregulated and enriched pathways in the DKO mice included DNA replication, DNA damage response, DNA repair, and RNA processing. Interestingly, the majority of upregulated genes in the enriched sections of the four shared pathways contain E2f binding site(s) in their promoters, suggesting that Rb and E2F8 largely repress those genes through the E2f binding sites. Collectively, our data suggest that Rb and E2F8 co-regulate E2F-responsive genes. Spleen Ter119+CD71high cells were sorted from WT, E2f8 KO, Rb KO and E2f8;Rb DKO mice

2014-05-30 | E-GEOD-52157 | biostudies-arrayexpress

E-GEOD-52157

Project description:Expression data from WT, E2f8 KO, Rb KO and Rb;E2f8 DKO spleen Ter19+CD71high sorted cells

2014-07-30 | E-GEOD-52157 | ExpressionAtlas

Expression data from WT, E2f8 KO, Rb KO and Rb;E2f8 DKO spleen Ter19+CD71high sorted cells

2014-05-30 | GSE52157 | GEO

Mus musculus

Project description:Expression data from control, Rb KO and Rb/Myc DKO tissues (villi and crypts)

| PRJNA242200 | ENA

Mus musculus

Project description:Expression data from miR-142 WT and KO spleen and bone marrow

| PRJNA338611 | ENA

RNA-Seq JunB WT and KO Tregs Mus musculus

Project description:To understand the mechanisms through which JunB regulates Tregs-mediated immune regulation, we examined the global gene expression profiles in the JunB WT and KO Tregs by performing RNA sequencing (RNA-seq) analysis.

2019-05-07 | GSE129060 | GEO

Mus musculus

Project description:RNA expression at spleen of WT and miR-142 KO mice

| PRJDB4295 | ENA

Bidirectional Introgression between Mus musculus domesticus and Mus spretus.

Project description: Not available

| S-EPMC8784167 | biostudies-literature

Mus musculus

Project description:Spleen response following malaria infection in WT and miR-155 KO mice.

| PRJNA287151 | ENA

Gene expression in mouse splenic CD4+CD25+ (Treg) cells from Ikzf2-/-, Ikzf4-/- and double Ikzf2-/-Ikzf4-/- (dKO) mice

Project description:CD4+CD25+ cells were sorted from the spleen of 6-7 week old mice WT, Ikzf4-/- and dKO mice (group 1) were processed separately from a a second group (group2) containing Ikzf2-/- and their WT controls. Group 1 originates from an ultra clean sterile bioBubble, while group 2 originates from a specific pathogne free facility. In each group 3 samples were analyzed for each genotype.

2023-10-24 | GSE162023 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data