Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

E-GEOD-52157

ABSTRACT: Expression data from WT, E2f8 KO, Rb KO and Rb;E2f8 DKO spleen Ter19+CD71high sorted cells

OTHER RELATED OMICS DATASETS IN: PRJNA227047

PROVIDER: E-GEOD-52157 | ExpressionAtlas | 2014-07-30

REPOSITORIES: ExpressionAtlas

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	E-GEOD-52157-analysis-methods.tsv	Tabular
	E-GEOD-52157-atlasExperimentSummary.Rdata	Rdata
	E-GEOD-52157-configuration.xml	Xml
	E-GEOD-52157-percentile-ranks.tsv	Tabular
	E-GEOD-52157.condensed-sdrf.tsv	Tabular

Items per page:

1 - 5 of 92

Similar Datasets

Expression data from WT, E2f8 KO, Rb KO and Rb;E2f8 DKO spleen Ter19+CD71high sorted cells

Project description:To understand molecular mechanisms underlying the synergy of Rb loss and E2F8 loss, we used gene expression profiling to assess molecular changes in Mx1-Cre-mediated knockout (KO) mice using RNA isolated from sorted Ter119+CD71high Erythroblasts. The top four upregulated and enriched pathways in the DKO mice included DNA replication, DNA damage response, DNA repair, and RNA processing. Interestingly, the majority of upregulated genes in the enriched sections of the four shared pathways contain E2f binding site(s) in their promoters, suggesting that Rb and E2F8 largely repress those genes through the E2f binding sites. Collectively, our data suggest that Rb and E2F8 co-regulate E2F-responsive genes. Spleen Ter119+CD71high cells were sorted from WT, E2f8 KO, Rb KO and E2f8;Rb DKO mice

2014-05-30 | E-GEOD-52157 | biostudies-arrayexpress

Mus musculus

Project description:Expression data from WT, E2f8 KO, Rb KO and Rb E2f8 DKO spleen Ter19+CD71high sorted cells

| PRJNA227047 | ENA

E-GEOD-71312

Project description:Expression data from WT Col-0 and the pdx1.3 ko mutant of Arabidopsis

2015-09-18 | E-GEOD-71312 | ExpressionAtlas

E-GEOD-45826

Project description:Expression data from sorted control and Pygo2-null mouse mammary stem/basal cells

2015-07-13 | E-GEOD-45826 | ExpressionAtlas

E-GEOD-48786

Project description:Expression data from endothelial cells sorted from breast cancer cells MDA-MB231 as compared with normal endothelial cells