Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Fluoribacter dumoffii strain:Hamilton

ABSTRACT: Legionella dumoffii str. Hamilton genome sequencing

PROVIDER: PRJNA270251 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR1709077_1.fastq.gz	Fastqsanger.gz
	SRR1709077_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 2 of 2

Similar Datasets

Fluoribacter gormanii strain:ATCC 33342 | isolate:ATCC 33342

Project description:Legionella gormanii ATCC 33342 genome sequencing

| PRJNA329785 | ENA

Analysis of the genes and mechanisms responsible for the cytotoxicity of the Legionella Ofk308 strain in the Tetrahymena host

Project description:Legionella pneumophila, an intracellular pathogen responsible for the pneumonia-like Legionnaires’ disease in humans, inhabits aquatic environments, including man-made water systems such as water fountains, foot spas, and tap water, and exists as part of biofilms or as a protozoan parasite. As a bacterivore, Tetrahymena thermophila provides a favorable environment for Legionella to establish a replicative niche (Legionella-containing vacuole; LCV) under environmental stress. Conversely, the L. pneumophila Ofk308 strain, isolated from an Ashiyu foot spa, has been found to be cytotoxic to the ciliate T. thermophila CU427. This study aimed to identify the cytotoxicity-related genes of Legionella and elucidate their mechanisms specific to the Tetrahymena host. A comparative analysis using RNA-sequencing was conducted with two Legionella strains, Philadelphia-1 and Ofk308, to select several candidate genes. Deletion mutants of Ofk308 were constructed by homologous recombination. Eight out of ten candidate gene deletion mutants were successfully generated. These mutants were analyzed for cytotoxicity against T. thermophila and intracellular bacterial growth at 2 h, 24 h, and 48 h postinfection. Among the deletion mutants, ∆vicinal oxygen chelate (VOC) and msrB/A exhibited reduced cytotoxicity. Furthermore, LCVs formed in T. thermophila infected with ∆VOC and msrB/A were smaller in size compared to those formed by the parental strain Ofk308, suggesting a role in both cytotoxicity and intracellular growth. Multiple factors contribute to the cytotoxicity exhibited by the Ofk308 strain in protozoan host cells, and gene expression analysis may reveal additional relevant factors.

2025-08-08 | GSE304426 | GEO

Legionella anisa str. Linanisette

Project description:Legionella anisa str. Linanisette Genome sequencing and assembly

| PRJNA174470 | ENA

Legionella pneumophila str. Corby

Project description:Legionella pneumophila str. Corby Genome sequencing and assembly

| PRJNA904548 | ENA

Legionella pneumophila subsp. pneumophila str. Hextuple_2q

Project description:Legionella pneumophila subsp. pneumophila str. Hextuple_2q Genome sequencing

| PRJNA72895 | ENA

Legionella pneumophila str. 121004

Project description:Legionella pneumophila str. 121004 Genome sequencing and assembly

| PRJNA214447 | ENA

Legionella pneumophila subsp. pneumophila str. Hextuple_3a

Project description:Legionella pneumophila subsp. pneumophila str. Hextuple_3a Genome sequencing

| PRJNA72897 | ENA

Methylome of Salmonella enterica subsp. Enterica serovar Javiana str. CFSAN001992 by PacBio SMRT Sequencing

Project description:Single-molecule read technologies allow for detection of epigenomic base modifications during routine sequencing by analysis of kinetic data during the reaction, including the duration between base incorporations at the elongation site (the "inter-pulse duration.") Methylome data associated with a closed de novo bacterial genome of Salmonella enterica subsp. enterica serovar Javiana str. CFSAN001992 was produced and submitted to the Gene Expression Omnibus. Single-sample sequencing and base modification detection of cultured isolate of a foodborne pathogen.

2013-03-15 | E-GEOD-45178 | biostudies-arrayexpress

Anoxygenic Photosynthesis and Dark Carbon Metabolism in the Purple Sulfur Bacterium “Thiodictyon syntrophicum“ nov. strain Cad16T

Project description:Strain Cad16T was previously shown to fix a major fraction of the bulk CO2 under both light and dark conditions and was suggested to be involved in Fe(II) driven aerobic metabolism in the lake Cadagno chemocline. However evidence on genomic and proteomic level was only fragmentary . In order to understand the biological functions expressed under phototrophic and chemotrophic growth conditions of str. Cad16T an in situ experiment conceived. It included cultures of str. Cad16T incubated in dialysis bags for three months while physiochemical conditions were monitored longitudinally. Upon sampling, physiological differences of str. Cad16T were compared utilizing quantitative proteomics in combination with CO2-uptake measurements.

2019-03-29 | PXD010641 | Pride

Fluoribacter gormanii strain:ATCC 33297

Project description:Fluoribacter gormanii strain:ATCC 33297 Genome sequencing and assembly

| PRJNA281301 | ENA